atastrophic events like the Asian tsunami of 2004, which killed nearly 300,000 people; the Haiti earthquake of 2010, which killed over 200,000; and most recently the earthquake in Nepal have demonstrated the urgent need for rapid response and a high level of preparedness during natural disasters. New aerospace technology including nanosatellites and unmanned aerial vehicles (drones) can provide a highly adaptable mechanism for on-demand communication, situational awareness, and even direct intervention as first responders, which can help to save thousands.Nanosatellites are a new class of low-cost modular space assets with the potential to quickly reconfigure and provide telecommunication and high-resolution imaging. For instance, Planet Labs completed a launch sequence of a swarm of 28 Earth-imaging CubeSats in March 2015, whereas companies including OneWeb, ComDev, and SpaceX envision even larger constellations. While satellites provide a global view and coordination, small low-cost drones can deliver first-aid kits and vital medicine and can track people or deploy sensors that can be attached to their bodies for tracking and monitoring of vital signs. Larger autonomous helicopters could then be optimally deployed to rescue the most severely injured and to deploy self-contained disaster relief packages. 1 To achieve such capabilities, it is necessary to develop navigation systems for robust operations in extreme weather and natural terrains, a technology that could be viable several years from now. REFERENCE 1. Dinas PC, Mueller C, Clark N, et al. Innovative methods for the benefit of public health using space technologies for disaster response. Disaster Med Public Health Prep.