The chapter presents simulation models for the analysis of centrifugal pumps, fans and positive displacement pumps. In centrifugal pumps based on the "sliding mesh" method, a CFD model was created to calculate the flow characteristics, and the pump operating parameters were determined at which an unfavourable phenomenon of cavitation occurs. In the case of a radial fan, the CFD model was used to determine the influence of inlet channel geometry on the efficiency of an industrial installation. The main purpose of the CFD simulation was to obtain the pressure distributions and determine the areas in which cavitation may occur. To investigate the flow phenomena that occur in external gear pumps and double-acting vane pumps, the "immersed solid" method was used. The results of 2D and 3D simulation studies for various operating parameters of pumps have been presented.