Inpatient treatment of trekkers and Nepalese workers in the high-altitude environment of Mt. Everest Region 1996–2011: A retrospective analysis

Kühn, Christian; Apel, Christian; Bertsch, Daniela; Graß, Maren; Gschwandtl, Carina; Hundt, Nina; Müller-Ost, Miriam; Risse, Julia; Schmitz, S.; Sherpa, Kami; Timmermann, Lars; Giet, Michsel van der; Giet, Simone van der; Wernitz, Knut; Morrison, Alistair; Küpper, Thomas

doi:10.1016/j.tmaid.2018.11.012

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Cited by 4 publications

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“…Þessu til viðbótar má hreinsa vatn án utanaðkomandi efna, til daemis með notkun lampa sem gefa frá sér útfjólublátt ljós eða með notkun sólarorku. Algengt er að fá niðurgang í háfjallaferðum og kviðverkir geta oft fylgt honum 74. Í slíkum aðstaeðum er mikilvaegt að drekka vel af vökva með sykri og söltum.…”

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Hæðarveiki og tengdir sjúkdómar

Guðbjartsson

Sigurðsson

Gottfreðsson

et al. 2019

LBL

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Hæðarveiki og tengdir sjúkdómar

Guðbjartsson

Sigurðsson

Gottfreðsson

et al. 2019

LBL

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Challenges in the management of high-altitude illnesses and emergencies in Bhutan and Nepal

Dorji,

Giri,

Tshering

et al. 2023

Travel Medicine and Infectious Disease

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Research Progress on the Mechanism of Intestinal Barrier Damage and Drug Therapy in a High Altitude Environment

Cheng

Sun

Zhao

et al. 2024

CDD

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The plateau is a typical extreme environment with low temperature, low oxygen and high ultraviolet rays. The integrity of the intestinal barrier is the basis for the functioning of the intestine, which plays an important role in absorbing nutrients, maintaining the balance of intestinal flora, and blocking the invasion of toxins. Currently, there is increasing evidence that high altitude environments can enhance intestinal permeability and disrupt intestinal barrier integrity. This article mainly focuses on the regulation of the expression of HIF and tight junction proteins in the high altitude environment, which promotes the release of pro-inflammatory factors, especially the imbalance of intestinal flora caused by the high altitude environment. The mechanism of intestinal barrier damage and the drugs to protect the intestinal barrier are reviewed. Studying the mechanism of intestinal barrier damage in high altitude environment is not only conducive to understanding the mechanism of high altitude environment affecting intestinal barrier function, but also provides a more scientific medicine treatment method for intestinal damage caused by the special high altitude environment.

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Inpatient treatment of trekkers and Nepalese workers in the high-altitude environment of Mt. Everest Region 1996–2011: A retrospective analysis

Cited by 4 publications

References 30 publications

Hæðarveiki og tengdir sjúkdómar

Hæðarveiki og tengdir sjúkdómar

Challenges in the management of high-altitude illnesses and emergencies in Bhutan and Nepal

Research Progress on the Mechanism of Intestinal Barrier Damage and Drug Therapy in a High Altitude Environment

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