Integrated optofluidics: A new river of light

Monat, Christelle; Domachuk, P.; Eggleton, Benjamin J.

doi:10.1038/nphoton.2006.96

Cited by 902 publications

(566 citation statements)

References 113 publications

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“…The mixing, switching and transport of liquids can be achieved in a highly automated and integrated fashion on a microfluidic device, which is impossible with bulk liquid handing systems. For more comprehensive discussions of the general idea of optofluidcs, the readers are referred to Psaltis et al (2006) and Monat et al (2007). Third and probably the most important feature of the optofluidic dye lasers is their ability to integrate with other optical and microfluidic functions to build complete ''labon-a-chip'' systems.…”

Section: Introductionmentioning

confidence: 99%

Optofluidic dye lasers

Psaltis

2007

Microfluid Nanofluid

159

110

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Optofluidic dye lasers are microfabricated liquid dye lasers enabled by the microfluidics technology. The integration of dye lasers with microfluidics not only facilitates the implementation of complete ''lab-on-a-chip'' systems, but also allows the dynamical control of the laser properties which is not achievable with solid-state optical components. We review the recent demonstrations of onchip liquid dye lasers and some of the pre-microfluidics era microscopic dye lasers which are also amenable to microfluidic implementation. Potential applications and future directions are discussed.

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Section: Introductionmentioning

confidence: 99%

Optofluidic dye lasers

Psaltis

2007

Microfluid Nanofluid

159

110

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“…As we will see in Section 7.3, the small dimensions inherent to micro-optics allow the use of fl uids in ways not possible in classical macro-optics [16] . Liquid lenses, waveguides and prisms have been realized using a variety of fl uids, manipulated using the technologies of micro-fl uidics.…”

Section: Liquids Dielectrics and Othermentioning

confidence: 99%

“…Using liquids both as optical media and as actuation means for components has also led to a variety of creative components and systems ( [3] , Chapter 13; [16,54] ). Among the types of devices demonstrated are fl uidic microlenses [53] ; fl uidic microscopes [55] ; fl uidic attenuators and irises [56,57] ; fl uidic microprisms [58] ; and even fl uidic lasers [59] .…”

Section: Optofl Uidicsmentioning

confidence: 99%

Micro-optics: a micro-tutorial

Zappe

2012

Advanced Optical Technologies

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Micro-optics represents a rich discipline with many features not found in classical optics. Yet micro-optics is not merely ' small optics ' . Using the technologies of microfabrication, entirely new fabrication processes, new materials and new types of optical devices have been conceived. Here, we provide a brief introduction to the fi eld, discussing a variety of miniaturized optical components, as well as the materials from which they are made and the novel technologies used to fabricate them. Designed as a tutorial, this brief pr é cis includes adequate literature references to guide the interested reader to more in-depth treatments.

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“…Optical analysis can also be used to measure the size and morphology from the angular scatter of particles and offers more information on phenotype than impedance sensing as a range of fluorescently tagged antibodies with different emission peaks can be used to discriminate between cell types. While impedance based detection can be readily integrated into planar chip configurations using planar electrodes [4] integration strategies for optofluidics have not been fully developed [5]. A popular approach is to insert optical fibres into microchannels aligned with the microfluidics [6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Integrated optical waveguides and inertial focussing microfluidics in silica for microflow cytometry applications

Butement

Hunt²,

Rowe

et al. 2016

J. Micromech. Microeng.

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A key challenge in the development of a microflow cytometry platform is the integration of the optical components with the fluidics as this requires compatible micro-optical and microfluidic technologies. In this work a microflow cytometry platform is presented comprising monolithically integrated waveguides and deep microfluidics in a rugged silica chip. Integrated waveguides are used to deliver excitation light to an etched microfluidic channel and also collect transmitted light. The fluidics are designed to employ inertial focussing, a particle positioning technique, to reduce signal variation by bringing the flowing particles onto the same plane as the excitation light beam. A fabrication process is described which exploits microelectronics mass production techniques including: sputtering, ICP etching and PECVD. Example devices were fabricated and the effectiveness of inertial focussing of 5.6 µm fluorescent beads was studied showing lateral and vertical confinement of flowing beads within the microfluidic channel. The fluorescence signals from flowing calibration beads were quantified demonstrating a CV of 26%. Finally the potential of this type of device for measuring the variation in optical transmission from input to output waveguide as beads flowed through the beam was evaluated.

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Integrated optofluidics: A new river of light

Cited by 902 publications

References 113 publications

Optofluidic dye lasers

Optofluidic dye lasers

Micro-optics: a micro-tutorial

Integrated optical waveguides and inertial focussing microfluidics in silica for microflow cytometry applications

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