Interactions between and can induce apoptosis and cell cycle arrest in mouse RAW264.7 macrophages

Penttinen, Piia; Pelkonen, Jukka; Huttunen, Kati; Toivola, Mika; Hirvonen, Maija-Riitta

doi:10.1016/j.taap.2004.07.002

Cited by 28 publications

(24 citation statements)

References 32 publications

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“…In these damp environments, actinobacteria frequently cohabit with fungal genera associated with moisture damage, such as Stachybotrys and Aspergillus. Research evaluating the impact of such BFIs in cell lines indicates a significant potential for synergistic effects between these bacteria and fungi on cytotoxicity and mammalian inflammatory responses (170,267,304,305). While mixed bacterial-fungal communities have been shown to have detrimental effects on human health, to our knowledge, there have been no reports describing the roles of intrahyphal bacteria in fungal infections of humans.…”

Section: Roles In Host Health and Diseasementioning

confidence: 99%

Bacterial-Fungal Interactions: Hyphens between Agricultural, Clinical, Environmental, and Food Microbiologists

Frey‐Klett

Burlinson

Deveau

et al. 2011

Microbiol Mol Biol Rev

736

531

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SUMMARY Bacteria and fungi can form a range of physical associations that depend on various modes of molecular communication for their development and functioning. These bacterial-fungal interactions often result in changes to the pathogenicity or the nutritional influence of one or both partners toward plants or animals (including humans). They can also result in unique contributions to biogeochemical cycles and biotechnological processes. Thus, the interactions between bacteria and fungi are of central importance to numerous biological questions in agriculture, forestry, environmental science, food production, and medicine. Here we present a structured review of bacterial-fungal interactions, illustrated by examples sourced from many diverse scientific fields. We consider the general and specific properties of these interactions, providing a global perspective across this emerging multidisciplinary research area. We show that in many cases, parallels can be drawn between different scenarios in which bacterial-fungal interactions are important. Finally, we discuss how new avenues of investigation may enhance our ability to combat, manipulate, or exploit bacterial-fungal complexes for the economic and practical benefit of humanity as well as reshape our current understanding of bacterial and fungal ecology.

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Section: Roles In Host Health and Diseasementioning

confidence: 99%

Bacterial-Fungal Interactions: Hyphens between Agricultural, Clinical, Environmental, and Food Microbiologists

Frey‐Klett

Burlinson

Deveau

et al. 2011

Microbiol Mol Biol Rev

736

531

View full text Add to dashboard Cite

show abstract

“…In fact, species of the genus Streptomyces have been isolated from moisture-damaged buildings [19] in which the occupants have experienced symptoms. Studies conducted in mouse cell lines indicate that the spores of Streptomyces californicus express cytotoxic, cytostatic and genotoxic properties [20,21,22]. Furthermore, in mouse models, increased proinflammatory cytokine secretion, inflammation and systemic immunotoxicity have been reported following instillation of S. californicus spores [23,24].…”

Section: Discussionmentioning

confidence: 99%

High Indoor Microbial Levels Are Associated with Reduced Th1 Cytokine Secretion Capacity in Infancy

Lappalainen¹,

Hyvärinen²,

Hirvonen³

et al. 2012

Int Arch Allergy Immunol

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Background: Exposure to microbes and their components may affect the maturation of the immune system.We examined the association of house dust microbial content with cytokine-producing capacity at birth and at the age of 1 year. Methods: Production of TNF-α, IFN-γ, IL-5, IL-8 and IL-10 at birth (n = 228) and at the age of 1 year (n = 200) following 24- and 48-hour whole-blood stimulation with staphylococcal enterotoxin B (SEB), lipopolysaccharide and the combination of phorbol ester and ionomycin was measured. Concentrations of ergosterol (marker for fungal biomass), muramic acid (marker for Gram-positive bacteria) and 3-hydroxy fatty acids with a carbon chain length from 10 to 14 (marker for Gram-negative bacteria) in living room floor dust were analyzed using gas chromatography-tandem mass spectrometry. Five single microbial species or groups were determined using a quantitative polymerase chain reaction method. Results: A high total level of the studied Gram-positive bacteria in general or Mycobacterium spp. in house dust was associated with decreased SEB-stimulated IFN-γ production, especially at the age of 1 year. The total level of indoor fungi analyzed (Penicillium spp., Aspergillus spp. and Paecilomyces variotii group, Trichoderma viride/atroviride/koningii,Wallemia sebi) was also inversely associated with IFN-γ production at the age of 1 year, but this association did not remain significant after adjustment for potential confounders. A few associations were found between microbial exposures and other measured cytokines. Conclusions: High indoor microbial exposures may affect immune development in early life by reducing T helper type 1 cytokine secretion capacity. The observed hyporesponsiveness may reflect the adaptation of the immune system to environmental antigens. In future, more attention should be paid especially to the immunomodulatory role of exposures to Gram-positive bacteria.

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“…Several researchers have found that products obtained by co-culture and mixed culture had relatively higher nutritive value than the product obtained by single culture fermentation (Penttinen et al 2005;Oh et al 2007;Melikoglu et al 2013). Increased production of cellulases was found by a co-culture of Aspergillus niger and Trichoderma reesei (Ahmed and Vermette 2008).…”

Section: Introductionmentioning

confidence: 99%

Effect of sequential bio-processing conditions on the content and composition of vitamin K2 and isoflavones in fermented soy food

2015

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In the present research, effect of sequential addition of Bifidobacterium bifidum, Bacillus subtilis and Rhizopus oligosporus on content and composition of vitamin K 2 and isoflavones in fermented soy foods have been investigated. Initially, soybeans were fermented with B. bifidum; then this fermented mass was re-fermented with co-culture of B. subtilis and R. oligosporus. The evolved sequence of microbes inoculation tended towards significantly (p <0.5) higher enzymes levels (126.16±2.23 IU/mg lipase, 36.52± 1.25 IU/mg phytase and 8.52±1.12 IU/mg β-glucosidase); maximum menaquinone-7 production (9.3±1.27 μg/g); and isoflavone content (84.64±1.97 % daidzein, 99.29±0.86 % genistein, 96.42±1.32 % glycitein) after 72 h of solid-state fermentation. The study showed that co-fermentation of soybean with different microbes in a particular sequence can enhance nutritional value batter than the mono-culture fermentation due to the positive correlation between enzymes (lipase, phytase, β-glucosidase) levels, menaquinone-7 and soy isoflavones content.

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Interactions between and can induce apoptosis and cell cycle arrest in mouse RAW264.7 macrophages

Cited by 28 publications

References 32 publications

Bacterial-Fungal Interactions: Hyphens between Agricultural, Clinical, Environmental, and Food Microbiologists

Bacterial-Fungal Interactions: Hyphens between Agricultural, Clinical, Environmental, and Food Microbiologists

High Indoor Microbial Levels Are Associated with Reduced Th1 Cytokine Secretion Capacity in Infancy

Effect of sequential bio-processing conditions on the content and composition of vitamin K2 and isoflavones in fermented soy food

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