Interactions of ethylenediamine tetraacetic acid with sodium hypochlorite in aqueous solutions

Grawehr, M.; Sener, Beatrice; Waltimo, Tuomas; Zehnder, Matthias

doi:10.1046/j.1365-2591.2003.00670.x

Cited by 190 publications

(195 citation statements)

References 25 publications

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“…In a literature review, it is mentioned that EDTA reduces the tissuedissolving effect of sodium hypochlorite which indicates the requirement of its use for a final rinse. 26,27 In this study, in terms of to reflect the clinical simulation, EDTA was applied following sodium hypochlorite irrigation for a final rinse which has found to be more effective in the removal of remaining root canal filling material when compared with the use of sodium hypochlorite alone or sodium hypochlorite combined with calcium hydroxide. remnants were significantly decrease at the cervical part of the root canals in favor of the EDTA and sodium hypochlorite group.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of Ethylenediamine Tetraacetic Acid and Calcium Hydroxide in the Removal of Root Canal Filling During Retreatment

Güven¹

2017

Cumhuriyet Dental Journal

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A B S T R A C TObjective: To compare the effect of Ethylenediamine tetraacetic acid (EDTA) and calcium hydroxide [Ca(OH)2] in the removal of root canal filling material during retreatment procedure.Methodology: Eighty extracted, single-rooted human teeth were used. Root canals were shaped with a crown-down technique using Ni-Ti rotary instruments (ProTaper, Dentsply Maillefer, Switzerland) and filled with a cold lateral condensation method. AH Plus was used as a sealer. After filling, the teeth were divided into 4 groups and root fillings were removed by ProTaper Universal rotary retreatment system. In each group different irrigation and disinfection protocols were followed; Group I. Sodium hypochlorite (5.25%) + EDTA (17%-1 min.) Group II. Sodium hypochlorite (5.25%) Group III. Sodium hypochlorite (5.25%) + Ca (OH)2 Group IV. Sodium hypochlorite (5.25%) + Ca(OH)2 + EDTA (17%-1 min.). Irrigation with 17% EDTA was performed only before D3-Retreatment instrumentation in all groups. AutoCAD system was used to detect the amount of residual root canal filling material. The results were statistically analyzed by SPSS (Statistical Package for Social Sciences) for Windows 15.0, one way ANOVA and Tukey's HSD tests. The significance was evaluated at the level of p<0.05. Results:The amount of the remnant filling material in the root canals retreated in Group I was less than the amount of the material in Group II (p<0.01) and Group III (p<0.05). There was no significant difference observed between the other groups in terms of the quantity of the remnant root canal filling materials (p>0.05).Conclusions: Irrigating the canals with EDTA enhanced the removal of root canal filling during retreatment. However, disinfecting the canals with Ca(OH)2 had no effect in the removal of filling material.

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Section: Discussionmentioning

confidence: 99%

Efficacy of Ethylenediamine Tetraacetic Acid and Calcium Hydroxide in the Removal of Root Canal Filling During Retreatment

Güven¹

2017

Cumhuriyet Dental Journal

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“…RC-Prep includes EDTA as a chelating agent [6] [7], which facilitates root canal preparation. Furthermore, urea peroxide is also included to generate oxygen in combination with sodium hypochlorite, which has potentially hazardous effects [8].…”

Section: Discussionmentioning

confidence: 99%

Subcutaneous Emphysema Caused by Sodium Hypochlorite plus RC-Prep

Tokuda¹,

Kawakami²,

Morimoto-Yamashita³

et al. 2014

OJST

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Introduction: "RC-Prep", a chemo-mechanical preparation for root canals, includes EDTA and urea peroxide as ingredients. For lubrication and its chelating effect, RC-Prep is useful as an adjunct in root canal enlargement. Furthermore, its cleaning action, due to its foaming properties in combination with sodium hypochlorite, can be useful in root canal treatment in many situations. Methods: In a case of upper gingiva swelling, we used sodium hypochlorite with RC-Prep in the treatment of an infected root canal of the left maxillary premolar at the first visit. Within 2 min after use, the patient's face became swollen. We kept the root canal open, and conducted a CT scan to investigate. Results: We diagnosed subcutaneous emphysema and prescribed 1 week of pain killers and antibiotics. The pain and swelling in the face finally resolved at 11 days after the incident. Conclusions: The cause of the emphysema was considered to have been the use of a sodium hypochlorite solution after using RC-Prep for an opened root apex.

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“…Grawehr et al found that a solution of EDTA mixed with NaOCl retained calcium-binding capacity, but showed a sudden and rapid decrease in the amount of chlorine in NaOCl, significantly reducing the ability of NaOCl to degrade tissue (21). Many mishaps, such as the splashing of NaOCl into the patient's or dentist's eye, damaging of the patient's clothes, extrusion of NaOCl beyond the apical foramen, inadvertent injection of irrigants instead of anesthesia, or allergic reaction to the irrigation solution, can occur during root canal treatment (22).…”

Section: Interactions Of Naoclmentioning

confidence: 99%

Endodontic Irrigation Solutions: A Review

Topbaş

Adıgüzel

2017

Int Dent Res

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The goal of endodontic treatment is to remove all the vital and necrotic tissues, microorganisms and microbial byproducts from root canal system. This goal can be achieved through chemical and mechanical debridement of root canals. This article narrates the specifics and requirements of the irrigation solutions. Sodium hypochlorite is proposed as the primary irrigant by virtue of its organic tissue dissolution capacity and broad antimicrobial properties. On the other hand, chelation solutions are recommended as auxiliary solutions to remove the smear layer or to hinder its formation on dentin surface. Thus, it's hoped that sealers and root canal fillers can penetrate to dentin tubules and obturate the canals hermetically. There are new studies on traditional irrigants especially on some irrigants that can replace sodium hypoclorite. This article reviews the new irrigants which can be used in future endodontic practice, and their advantages and limitations. Moreover, actions and interactions of recently used irrigants are adverted.

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Interactions of ethylenediamine tetraacetic acid with sodium hypochlorite in aqueous solutions

Cited by 190 publications

References 25 publications

Efficacy of Ethylenediamine Tetraacetic Acid and Calcium Hydroxide in the Removal of Root Canal Filling During Retreatment

Efficacy of Ethylenediamine Tetraacetic Acid and Calcium Hydroxide in the Removal of Root Canal Filling During Retreatment

Subcutaneous Emphysema Caused by Sodium Hypochlorite plus RC-Prep

Endodontic Irrigation Solutions: A Review

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