Vehicular communication is gradually evolving from the rudimentary data exchange techniques to innovative, efficient, and large-scale communication platform. The future vehicular networks aim to offer new services and achieve massive connectivity with the aid of advanced wireless communication techniques. In this regard, one of the emerging paradigms is non-orthogonal multiple access (NOMA) which holds the promise to meet the resource-intensive demands of future networks. Due to this reason, the applications of NOMA are being investigated by the researcher of academia and industry alike. This article aims to build on the state-of-the-art by providing a novel multiobjective optimization framework for vehicle-to-infrastructure (V2I) communications. Specifically, this work aims to improve upon the sum-rate and energy efficiency of uplink NOMA-enabled V2I communications. The formulated problem is based on the tradeoff between sum-rate and total transmit power while maintaining the quality of service (QoS) requirements of the network. To provide a reliable solution, a multiobjective optimization framework has been proposed by applying the weighted-sum method and handle joint metrics of sum-rate maximization and total transmit power minimization. Extensive simulations have been performed to validate the superiority of the proposed framework against conventional benchmark techniques. The results clearly indicate that the proposed framework is feasible for NOMA-enabled V2I communication and can be scaled up for practical implementation. INDEX TERMS Non-orthogonal multiple access, multiobjective optimization, QoS, vehicular communication.