Whenever the response of an animal is altered by adding an extra stimulus to several stimuli already affecting the animal, the response may be changed in one of three possible ways: a separate response may be elicited by the extra stimulus; or any responses concomitant with the extra stimulus may be facilitated by it; or a concomitant response may be inhibited or decreased in strength. These possibilities can be restated summarily as a specific question: does a rat, stimulated to swim in a tank of water by reduction of the water temperature to a few degrees below its body temperature, alter its speed or style of swimming when a loud sound is added to the pattern of stimuli reaching it?The problem stated in this question would be classified by some persons under the somewhat ambiguous label of attention. When they classify the problem thus it resembles other problems such as distraction, fluctuation and duration of attention also arbitrarily classified under this obscure heading. These resemblances between the various problems of "attention" are apparent not so much in the behavior to which those names refer as in the physiological concomitants underlying that behavior. When regarded from a theoretical physiological point of view the problem of elicitation of facilitated or inhibited responses by multiple stimuli seems to be intimately related to the problems of crossconditioning, 2 prior entry, span of attention and other problems involving the effects of multiple and secondary stimuli on response.Having suggested some of the systematic implications of the problem of response due to multiple stimuli, it will be desirable