Internally structured pickering emulsions stabilized by clay mineral particles

Guillot, Samuel; Bergaya, F.; Azevedo, Christine de; Warmont, Fabienne; Tranchant, Jean‐François

doi:10.1016/j.jcis.2009.01.026

Cited by 86 publications

(51 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The apparent reason is that the toxicity of pristine carbon nanomaterials is presumed to be greatly reduced by coating them with the lipid molecules, which are already biogenic materials. Similar efforts were also made by other researchers who managed to stabilize O/W nanostructured emulsions using silica nanoparticles [72] and laponite or montmorillonite clay platelets [80,130,131]. As mentioned earlier, we were also able to construct lipid-hydrogel hybrid systems and demonstrate their potential for loading and release of functional molecules in a sustained manner [128] (Figure 8).…”

Section: Nano-hybrid Systems Based On Lipid Nanostructuressupporting

confidence: 76%

Lipid Self-Assemblies and Nanostructured Emulsions for Cosmetic Formulations

Kulkarni

2016

Cosmetics

View full text Add to dashboard Cite

A majority of cosmetic products that we encounter on daily basis contain lipid constituents in solubilized or insolubilized forms. Due to their amphiphilic nature, the lipid molecules spontaneously self-assemble into a remarkable range of nanostructures when mixed with water. This review illustrates the formation and finely tunable properties of self-assembled lipid nanostructures and their hierarchically organized derivatives, as well as their relevance to the development of cosmetic formulations. These lipid systems can be modulated into various physical forms suitable for topical administration including fluids, gels, creams, pastes and dehydrated films. Moreover, they are capable of encapsulating hydrophilic, hydrophobic as well as amphiphilic active ingredients owing to their special morphological characters. Nano-hybrid materials with more elegant properties can be designed by combining nanostructured lipid systems with other nanomaterials including a hydrogelator, silica nanoparticles, clays and carbon nanomaterials. The smart materials reviewed here may well be the future of innovative cosmetic applications.

show abstract

Section: Nano-hybrid Systems Based On Lipid Nanostructuressupporting

confidence: 76%

Lipid Self-Assemblies and Nanostructured Emulsions for Cosmetic Formulations

Kulkarni

2016

Cosmetics

View full text Add to dashboard Cite

show abstract

“…Although planar fluid bilayer is the most common nanostructure formed by amphiphilic lipid molecules in presence of water, other structures such as hexagonal and cubic are also commonly observed 20,41,42 . The type of nanostructure formed depend upon the lipids' molecular shape structure, the lipid composition in water as well as on the physico-chemical conditions employed such as temperature and pressure 43 , clay [47][48][49] and carbon nanotubes 50 for the stabilization of aforementioned emulsions, suitably termed as Pickering 51 or Ramsden-Pickering emulsions 52 .…”

Section: Introductionmentioning

confidence: 99%

Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes

Patil-Sen

Sadeghpour

Rappolt

et al. 2016

JoVE

View full text Add to dashboard Cite

We present a facile method to prepare nanostructured lipid particles stabilized by carbon nanotubes (CNTs). Single-walled (pristine) and multiwalled (functionalized) CNTs are used as stabilizers to produce Pickering type oil-in-water (O/W) emulsions. Lipids namely, Dimodan U and Phytantriol are used as emulsifiers, which in excess water self-assemble into the bicontinuous cubic Pn3m phase. This highly viscous phase is fragmented into smaller particles using a probe ultrasonicator in presence of conventional surfactant stabilizers or CNTs as done here. Initially, the CNTs (powder form) are dispersed in water followed by further ultrasonication with the molten lipid to form the final emulsion. During this process the CNTs get coated with lipid molecules, which in turn are presumed to surround the lipid droplets to form a particulate emulsion that is stable for months. The average size of CNT-stabilized nanostructured lipid particles is in the submicron range, which compares well with the particles stabilized using conventional surfactants. Small angle X-ray scattering data confirms the retention of the original Pn3m cubic phase in the CNT-stabilized lipid dispersions as compared to the pure lipid phase (bulk state). Blue shift and lowering of the intensities in characteristic G and G' bands of CNTs observed in Raman spectroscopy characterize the interaction between CNT surface and lipid molecules. These results suggest that the interactions between the CNTs and lipids are responsible for their mutual stabilization in aqueous solutions. As the concentrations of CNTs employed for stabilization are very low and lipid molecules are able to functionalize the CNTs, the toxicity of CNTs is expected to be insignificant while their biocompatibility is greatly enhanced. Hence the present approach finds a great potential in various biomedical applications, for instance, for developing hybrid nanocarrier systems for the delivery of multiple functional molecules as in combination therapy or polytherapy. Video LinkThe video component of this article can be found at

show abstract

“…Emulsions stabilized by solid particles are termed generally as Pickering [32] or Ramsden-Pickering [33] emulsions. Clay platelets [34], food hydrocolloids [35,36] and silica nanoparticles [37] are among such stabilizers, but in our recent work [18] we have employed carbon nanotubes (CNTs) for stabilizing nanostructured lipid particles. Pristine single-walled (SW) CNTs and functionalized multi-walled (MW) CNTs were employed successfully to stabilize internally selfassembled lipid particles [18].…”

Section: Introductionmentioning

confidence: 99%

Effect of fullerene on the dispersibility of nanostructured lipid particles and encapsulation in sterically stabilized emulsions

Kulkarni

Moinuddin

Agarwal

2016

Journal of Colloid and Interface Science

View full text Add to dashboard Cite

Abstract:We report on the effect of fullerenes (C60) on the stability of nanostructured lipid emulsions. These (oil-in-water) emulsions are essentially aqueous dispersions of lipid particles exhibiting self-assembled nanostructures at their cores. The majority of previous studies on fullerenes were focused on planar and spherical lipid bilayer systems including pure lipids and liposomes. In this work, fullerenes were interacted with a lipid that forms nanostructured dispersions of nonlamellar self-assemblies. A range of parameters including the composition of emulsions and sonication parameters were examined to determine the influence of fullerenes on in-situ and prestabilized lipid emulsions. We found that fullerenes mutually stabilize very low concentrations of lipid molecules, while other concentration emulsions struggle to stay stable or even to form at first instance; we provide hypotheses to support these observations. Interestingly though, we were able to encapsulate varying amounts of fullerenes in sterically stabilized emulsions. This step has a significant positive impact, as we could effectively control an inherent aggregation tendency of fullerenes in aqueous environments. These novel hybrid nanomaterials may open a range of avenues for biotechnological and biomedical applications exploiting properties of both lipid and fullerene nanostructures.

show abstract

Internally structured pickering emulsions stabilized by clay mineral particles

Cited by 86 publications

References 34 publications

Lipid Self-Assemblies and Nanostructured Emulsions for Cosmetic Formulations

Lipid Self-Assemblies and Nanostructured Emulsions for Cosmetic Formulations

Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes

Effect of fullerene on the dispersibility of nanostructured lipid particles and encapsulation in sterically stabilized emulsions

Contact Info

Product

Resources

About