Intestinal transit in anxiety and depression.

Gorard, Stephen; Gomborone, J. E.; Libby, G. W.; Farthing, M. J. G.

doi:10.1136/gut.39.4.551

Cited by 114 publications

(68 citation statements)

References 38 publications

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“…These findings are entirely consistent with the view that people who experience greater symptoms of constipation experience both higher levels of depression and impact upon their QoL. Previous research 210 indicates that anxiety is linked to increased gut transit time. Our results are at odds with this finding as our anxiety scores were also positively correlated with constipation symptoms.…”

Section: Pac-sym Pac-qol and Anxiety/depressionsupporting

confidence: 90%

See 1 more Smart Citation

LIFELAX – diet and LIFEstyle versus LAXatives in the management of chronic constipation in older people: randomised controlled trial

Speed

Heaven²,

Adamson³

et al. 2010

Health Technol Assess

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How to obtain copies of this and other HTA programme reports An electronic version of this title, in Adobe Acrobat format, is available for downloading free of charge for personal use from the HTA website (www.hta.ac.uk). A fully searchable DVD is also available (see below).Printed copies of HTA journal series issues cost £20 each (post and packing free in the UK) to both public and private sector purchasers from our despatch agents.Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per issue and for the rest of the world £3 per issue. How to order:-fax (with credit card details) -post (with credit card details or cheque) -phone during office hours (credit card only).Additionally the HTA website allows you to either print out your order or download a blank order form. Contact details are as follows:Synergie UK (HTA Department) Digital House, The Loddon Centre Wade Road Basingstoke Hants RG24 8QW Email: orders@hta.ac.uk Tel: 0845 812 4000 -ask for 'HTA Payment Services' (out-of-hours answer-phone service) Fax: 0845 812 4001 -put 'HTA Order' on the fax header Payment methods Paying by chequeIf you pay by cheque, the cheque must be in pounds sterling, made payable to University of Southampton and drawn on a bank with a UK address. Paying by credit cardYou can order using your credit card by phone, fax or post. SubscriptionsNHS libraries can subscribe free of charge. Public libraries can subscribe at a reduced cost of £100 for each volume (normally comprising 40-50 titles). The commercial subscription rate is £400 per volume (addresses within the UK) and £600 per volume (addresses outside the UK). Please see our website for details. Subscriptions can be purchased only for the current or forthcoming volume. How do I get a copy of HTA on DVD?Please use the form on the HTA website (www.hta.ac.uk/htacd/index.shtml). HTA on DVD is currently free of charge worldwide.The website also provides information about the HTA programme and lists the membership of the various committees. HTA LIFELAX -diet and LIFEstyle versus Health Technology Assessment is indexed and abstracted in Index Medicus/MEDLINE, Excerpta Medica/EMBASE, Science Citation Index Expanded (SciSearch NIHR Health Technology Assessment programmeT he Health Technology Assessment (HTA) programme, part of the National Institute for Health Research (NIHR), was set up in 1993. It produces high-quality research information on the effectiveness, costs and broader impact of health technologies for those who use, manage and provide care in the NHS. 'Health technologies' are broadly defined as all interventions used to promote health, prevent and treat disease, and improve rehabilitation and long-term care. The research findings from the HTA programme directly influence decision-making bodies such as the National Institute for Health and Clinical Excellence (NICE) and the National Screening Committee (NSC). HTA findings also help to improve the quality of clinical practice in the NHS indirectly in that they form a ...

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Section: Pac-sym Pac-qol and Anxiety/depressionsupporting

confidence: 90%

“…210 On the HADS, each item is marked on a four-point (0-3) response category. Scores can range from 0 to 21 for anxiety and 0 to 21 for depression.…”

Section: Pac-sym Pac-qol and Anxiety/depressionmentioning

confidence: 99%

LIFELAX – diet and LIFEstyle versus LAXatives in the management of chronic constipation in older people: randomised controlled trial

Speed

Heaven²,

Adamson³

et al. 2010

Health Technol Assess

View full text Add to dashboard Cite

show abstract

“…MDT-stress significantly increased the pulse rate and respiratory rate in this study. It is reported that anxiety is associated with increased bowel frequency, while depressed patients tend to be constipated (Gorard et al, 1996). It is also reported that anxiety correlated negatively with rectal mucosal blood flow (Emmanuel et al, 2001).…”

Section: Correlation Of Both Anxiety and Depression Scores And The Lfmentioning

confidence: 94%

Correlations between the responses of electrogastrograms, heart rate and respiratory rate to the stress of the mirror drawing test in human subjects

Homma

2006

J. Smooth Muscle Res.

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Original C o r r e l a t i o n s b e t w e e n t h e r e s p o n s e s o felectrogastrograms, heart rate and respiratory rate to the stress of the mirror drawing test in human subjects AbstractAn electrogastrogram (EGG) recorded on the skin is believed to reflect the electrical activity of the gastrointestinal tract. In this study, linear correlations were calculated for the EGG spectral frequencies and the power ratios, changes in heart and respiratory rate before and during mirror drawing test (MDT) stress and after having meals, with the changes in the sympathetic tone indicator (LF/HF) and HADS anxiety and depression scores in human subjects (n=48). Depression scores had a negative linear correlation with the EGG resting frequencies of the epigastric and supraumbilical 6 cpm groups (5.0-7.4 cpm). Anxiety scores had a positive linear correlation with the EGG area power ratio of the resting to MDT stress responses of the epigastric and infraumbilical 6 cpm groups (6 cpm area during MDT/that during fasting rest). The resting LF/HF had a positive linear correlation with the EGG area power ratio of the resting to MDT stress responses of the epigastric and infraumbilical 3 cpm groups (2.5-4.9 cpm). The resting LF/HF ratio had a negative correlation with the area power ratio of the resting to postprandial responses (postprandial power/resting power) in the epigatric, supraumbilical and infraumbilical 6 cpm groups. The resting LF/HF ratio had a positive linear correlation with the heart rate at rest and during MDT-stress. In contrast, the resting LF/HF ratio had a negative linear correlation with the respiratory rate at rest and during MDT-stress. EGGs of the surface electrical activities of the gastrointestinal tract were influenced by acute MDT-stress and their frequencies and their response power ratios were correlated linearly with anxiety scores, depression scores and the sympathetic tone indicator, the LF/HF ratio.

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“…Accordingly, even the topographic EGG maps based on absolute power itself and the absolute power ratios demonstrated gastric inhibition and colonic facilitation during MDT and postprandial epigastric facilitation. Approximate power ratios are indicated by symbol (<) and numerical figures, such as<1.0, 2.0, or <5, 8, 10, 20, and 30. stress significantly increased the bowel frequency, while depressed patients tended to be constipated (Gorard et al, 1996).…”

Section: Colonic Activitymentioning

confidence: 99%

Local differences in electrogastrographic responses to the stress of the mirror drawing test (MDT) as determined by multichannel electrogastrography

Homma

2012

J. Smooth Muscle Res.

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Electrogastrograms (EGGs) were recorded in human subjects (n=58) at 16 locations on the thoraco-abdominal surface before (at rest) and during the stress of the mirror drawing test (MDT) and after having a test meal. The power amplitude ratios and power content ratios of MDT to rest (MDT/rest) and postprandial state to rest (PPR/rest) were compared between gastric channels 5 and 8, and the infraumbilical channels 12, 13, 14, 15, and 16. Generally, the ratio of the 3-cpm group in channels 5 and 8 was lower than that of the infraumbilical channels 12-16 during MDT. In contrast, the ratios were higher in the epigastric channels than in the infraumbilical channels after a test meal. Significant differences between the epigstric and infraumbilical channels were found in the comparisons of the power content ratios. The infraumbilical channels were facilitated and the epigastric channels inhibited during MDT. After eating a meal, in contrast, the postprandial epigastric 3-cpm EGGs were facilitated. The epigastric 3-cpm EGG activity reflects gastric myoelectric activity, while the infraumbilical 3-cpm activity reflects that of the colon. Therefore, it is suggested that the acute stress of the MDT generally inhibited the gastric EGG and facilitated the colonic EGG, indicating gastric inhibition and colonic facilitation. The topographic EGG maps of the power content ratios and the absolute power ratios visually confirmed these findings.

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Intestinal transit in anxiety and depression.

Cited by 114 publications

References 38 publications

LIFELAX – diet and LIFEstyle versus LAXatives in the management of chronic constipation in older people: randomised controlled trial

LIFELAX – diet and LIFEstyle versus LAXatives in the management of chronic constipation in older people: randomised controlled trial

Correlations between the responses of electrogastrograms, heart rate and respiratory rate to the stress of the mirror drawing test in human subjects

Local differences in electrogastrographic responses to the stress of the mirror drawing test (MDT) as determined by multichannel electrogastrography

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