“…Continuous and intense nociceptive input from a damaged joint may contribute to sensitization by enhanced pain responses, the spread of pain to larger body areas, and outside the symptomatic joint [8,13,14]. Previous studies have demonstrated PPT to have a high relative reliability in various anatomical locations like knee [15,16], neck [17,18], and lower back [19,20] both in patients and in healthy humans. However, the reliability of PPT is influenced by factors such as gender, age, investigator and [19,21].…”