Intracellular antioxidant activity of Muntingia calabura leaves methanolic extract

Rahmawati, Aulia Nur; Astirin, Okid Parama; Pangastuti, Artini

doi:10.13057/nusbiosci/n100402

Cited by 5 publications

(3 citation statements)

References 22 publications

(34 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Berbagai macam penelitian terkait dengan potensi daun Kersen menunjukkan bahwa hampir seluruh bagian tumbuhan Kersen dapat dimanfaatkan. Rahmawati et al, (2018Rahmawati et al, ( , 2019 dalam penelitiannya menunjukkan bahwa ekstrak daun Kersen dapat menangkal radikal bebas dan mampu meningkatkan produksi kolagen. Hasil tersebut mendukung beberapa penelitian terdahulu terkait dengan kemampuan ekstrak daun Kersen sebagai antioksidan karena keberadaan senyawa flavonoid dan fenol di dalamnya (Balan et al, 2015;Marjoni et al, 2015;Zakaria et al, 2011Zakaria et al, , 2014.…”

Section: Pendahuluanunclassified

Uji Cemaran Mikroba dan Kapang Khamir Ekstrak Air Daun Muntingia calabura L. (Kersen)

Rahmawati¹,

Saryanti²,

Sari³

et al. 2022

Pharmacon

Self Cite

View full text Add to dashboard Cite

Kersen (Mutingia calabura L.) is a plant that can be used as a raw material for medicine because it has many medicinal benefits. Kersen as a medicinal raw material must pass a quality parameter testing process to be safe to use. One of the extract quality parameters is the total plate count for microbial (ALT) and yeast contamination (AKK). This study aims to evaluate the suitability of microbial and yeast contamination in the water extract of Kersen leaves to the applicable regulations. Extraction of Kersen leaves used maceration method with water solvent for 3 days with a ratio of 1:10. The results obtained from the water extract of Kersen leaves are organoleptically in the form of thick extract, dark brown in color, sour taste, bitter, and has a distinctive odor. The ALT value in the aqueous extract of cherry leaves was 8.4 x 10⁴ colonies/g. The AKK value in the aqueous extract of cherry leaves was 102 colonies/g which was reported as an approximate AKK value. The ALT and AKK values in the water extract of Kersen leaves meet the safety and quality requirements of traditional medicine.

show abstract

Section: Pendahuluanunclassified

Uji Cemaran Mikroba dan Kapang Khamir Ekstrak Air Daun Muntingia calabura L. (Kersen)

Rahmawati¹,

Saryanti²,

Sari³

et al. 2022

Pharmacon

Self Cite

View full text Add to dashboard Cite

show abstract

“…Malondialdehyde (MDA) merupakan suatu produk akhir peroksidasi lemak yang digunakan sebagai biomarker biologis peroksidasi lemak serta dapat menggambarkan derajat stres oksidatif. Sedangkan enzim SOD merupakan enzim antioksidan endogen utama yang mempunyai peranan penting secara langsung melindungi sel dari gangguan radikal bebas, dan secara tidak langsung memelihara keseimbangan oksigen yang bersifat toksik (Rahmawati et al, 2018). Eritrosit merupakan sel tubuh yang sangat vital fungsinya, eritrosit juga salah satu sel tubuh yang sangat rentan terhadap radikal bebas.…”

Section: Pendahuluanunclassified

Peningkatan daya tahan membran sel eritrosit dan jumlah sel eritrosit akibat latihan aerobik intensitas sedang

Yunus

Fathoni

Wahjuni³

2022

j. medikora

View full text Add to dashboard Cite

Penelitian ini bertujuan untuk mengkaji dan menganalisa besarnya peningkatan daya tahan membran sel eritrosit dan jumlah sel eritrosit akibat latihan aerobik intensitas sedang. Penelitian ini merupakan penelitian eksperimen semu dengan pendekatan kuantitatif, serta menggunakan rancangan pretest and posttest design. Populasi dalam penelitian ini adalah mahasiswa jurusan PKO FIK UM, dengan tehnik sampling menggunakan purposive sampling, serta jumlah sampel sebanyak 20 orang. Variabel bebas dalam penelitian ini yaitu latihan aerobik intensitas sedang. Latihan dilakukan dengan frekuensi 3 kali perminggu, selama 8 minggu dan durasi latihan 30 menit. Variabel terikat yaitu: 1) daya tahan membran sel eritrosit, dan 2) Jumlah sel eritrosit. Data variabel terikat pretest dan posttest dikumpulkan dengan teknik memeriksa darah vena yang dilaksanakan di laboratorium klinik Diagnostik Bromo Malang. Analisis data menggunakan teknik Uji t paired sample t test dengan menggunakan α 0,05. Hasil analisis data penelitian menunjukkan bahwa Fragiltas Osmotik sebagai indikator variabel daya tahan membran sel eritrosit Pretest 0,46±0,02% dan postest 0,43±0,02 %, P-value 0,029 α (0,05) sedangkan variabel jumlah sel eritrosit pretest 5,4580 ± 0,223 juta/uL dan postest 5,6230± 0,142 juta/uL,. P-value 0,021 α (0,05). Hal ini dapat disimpulkan bahwa terdapat peningkatan yang signifikan daya tahan membran sel eritrosit dan jumlah sel eritrosit akibat Latihan aerobik intensitas sedang.Increased endurance of erythrocyte cell membrane and erythrocyte cell number due to moderate intensity aerobic exerciseAbstractThis study aims to examine and analyze the magnitude of the increase in the endurance of the erythrocyte membrane and the number of erythrocyte cells due to moderate-intensity aerobic exercise. This research is a quasi-experimental research with a quantitative approach, and uses pretest and posttest design. The population in this study were students majoring in PKO FIK UM, with a sampling technique using purpusive sampling, and the number of samples was 20 people. The independent variable in this study was moderate intensity aerobic exercise. Exercises are carried out with a frequency of 3 times per week, for 8 weeks and the duration of the exercise is 30 minutes. The dependent variables are: 1) the durability of the erythrocyte cell membrane, and 2) the number of erythrocyte cells. The dependent variable data of pretest and posttest were collected by using the technique of examining venous blood which was carried out at the Bromo Diagnostic Clinic Malang. Data analysis used the paired sample t test technique using 0.05. The results of the analysis of research data showed that Osmotic Fragility as an indicator of the durability of the erythrocyte cell membrane. Pretest 0.46±0.02% and posttest 0.43±0.02%, P-value 0.029 (0.05) while the variable amount erythrocyte cells pretest 5.4580 ± 0.223 million/uL and posttest 5.6230 ± 0.142 million/uL, P-value 0.021 (0.05). It can be concluded that there is a significant increase in the endurance of the erythrocyte cell membrane and the number of erythrocytes due to moderate-intensity aerobic exercise.

show abstract

“…Malondialdehyde (MDA) is an end product of fat peroxidation that is used as a biological biomarker of fat peroxidation and can describe the degree of oxidative stress. While the SOD enzyme is the main endogenous antioxidant enzyme that has an important role directly protects cells from free radical interference, and indirectly maintains a toxic oxygen balance (Rahmawati et al, 2018). Erythrocytes are body cells that are very vital function, erythrocytes are also one of the body cells that are very vulnerable to free radicals.…”

Section: Introductionmentioning

confidence: 99%

Effect Of 8 Weeks Of Moderate-Intensity Aerobic Exercise On Increasing Erytocyte Cell Membrane Endurance And Erytrocyte Cell Count

Yunus¹

2023

AJHS

View full text Add to dashboard Cite

The purpose of this study was to examine and analyze the effect of 8 weeks of moderate-intensity aerobic exercise on increasing the endurance of erythrocyte cell membranes and the number of erythrocyte cells. This research is a pseudo-experimental research with a quantitative approach, and uses pretest and posttest design. The population in this study was students majoring in PKO FIK UM, with sampling techniques using purposive sampling, and the number of samples was 20 people. The independent variable in this study was moderate-intensity aerobic exercise. Exercise is done with a frequency of 3 times per week, for 8 weeks and the duration of exercise is 30 minutes. The dependent variables are: 1) the durability of erythrocyte cell membranes, and 2) the number of erythrocyte cells. Pretest and posttest dependent variable data were collected by venous blood checking techniques carried out in the Bromo Malang Diagnostic clinical laboratory. Data analysis using the paired sample t test technique using ? 0.05. The results of the analysis of research data showed that Osmotic Fragility as a variable indicator of erythrocyte cell membrane durability Pretest 0.46±0.04% and postest 0.43±0.06%, P-value 0.028 < ? (0.05) while variable number of erythrocyte cells pretest 5.4590 ± 0.223 million / uL and postest 5.6270± 0.142 million / uL,. P-value 0.022 < ? (0.05). It can be concluded the effect of 8 weeks of moderate intensity aerobic exercise can increase significantly on increasing the endurance of erythrocyte cell membranes and the number of erythrocyte cells

show abstract

Intracellular antioxidant activity of Muntingia calabura leaves methanolic extract

Cited by 5 publications

References 22 publications

Uji Cemaran Mikroba dan Kapang Khamir Ekstrak Air Daun Muntingia calabura L. (Kersen)

Uji Cemaran Mikroba dan Kapang Khamir Ekstrak Air Daun Muntingia calabura L. (Kersen)

Peningkatan daya tahan membran sel eritrosit dan jumlah sel eritrosit akibat latihan aerobik intensitas sedang

Effect Of 8 Weeks Of Moderate-Intensity Aerobic Exercise On Increasing Erytocyte Cell Membrane Endurance And Erytrocyte Cell Count

Contact Info

Product

Resources

About