Intracranial yolk sac tumor in an adult patient: MRI, diffusion-weighted imaging and 1H MR spectroscopy features

Macvanski, Marija; Ristic-Balos, Dragana; Vasić, Brankica; Lavrnić, Slobodan; Gavrilović, Svetlana; Milicevic, Mihajlo; Milenković, Sanja; Stošić-Opinćal, Tatjana

doi:10.2298/vsp1203277m

Cited by 10 publications

(3 citation statements)

References 21 publications

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“…In most cases, the onset of YST occurs in childhood and young adulthood. In the relevant English literature, there are only 5 reported cases of YST in patients over 35 years old (Table 1) (23)(24)(25)(26)(27). Our case represents the fourth-oldest patient with adult-onset yolk sac tumor reported worldwide.…”

Section: Discussionmentioning

confidence: 86%

Mixed Germ Cell Tumor with a Yolk Sac Tumor Component in the Medulla Oblongata of a 50-year-old Patient: A Case Report and Literature Review

et al. 2023

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Yolk sac tumor (YST) is a rare primary brain tumor that occurs almost exclusively in patients under 30 years old. Intracranial germ cell tumors are most frequently located in the pineal and suprasellar region. Medulla oblongata YSTs are particularly rare. Extragonadal YSTs may be difficult to diagnose because of their characteristics, such as the rarity and variety of growth patterns. Furthermore, they are known to have a very poor prognosis. We herein report a case of YST of the medulla oblongata in a 50-year-old woman. She was followed up for 18 months without any tumor recurrence.

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Section: Discussionmentioning

confidence: 86%

Mixed Germ Cell Tumor with a Yolk Sac Tumor Component in the Medulla Oblongata of a 50-year-old Patient: A Case Report and Literature Review

et al. 2023

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“…Although Magnetic Resonance Imaging is the imaging of choice, there are few specific radiological features for YST ( 13 ). But magnetic resonance diffusion weighted images and magnetic resonance spectroscopy was reported to be helpful in differentiation from other neoplasms ( 14 ). The final diagnosis of YSTs depends on the pathology examinations, Schiller-Duval body and is pathognomonic of YSTs.…”

Section: Discussionmentioning

confidence: 99%

Multifocal primary intracranial yolk sac tumor in an adult patient: a case report and literature review

Yang¹,

Wang²,

Chen³

et al. 2022

Transl Cancer Res TCR

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Background Yolk sac tumor is a type of germ cell tumor. It commonly arises in the gonads but sometimes can occur outside the gonads. Primary intracranial yolk sac tumors were very rare. It is always located in the pineal, suprasellar and posterior third ventricular region. The incidence of yolk sac tumor is estimated as less than 8% of all primary intracranial germ cell tumors. Multifocal primary intracranial yolk sac tumors have seldom been reported. Case Description Here we reported a 29 years old male patient with a sudden coma and a history of headaches for one month. Computed Tomography and magnetic resonance imaging of the head showed three masses located at the suprasellar region, pineal region and left temporal lobe separately. The mass at the left temporal lobe was successfully resected with emergency surgery, and decompressive craniectomy was also performed. Intraoperative findings revealed that the tumor was a solid mass with intra-tumoral haemorrhage. The pathology examination confirmed the diagnosis of yolk sac tumor. Hematoxylin and eosin staining clearly showed the Schiller-Duval body. Whole-brain radiotherapy was performed after the operation, and the patient died in a local hospital 11 months after the surgery. Conclusions We reported a case of multifocal primary intracranial yolk sac tumor in an adult patient. Then we reviewed the literature and discussed the treatment and diagnosis of patients with primary intracranial yolk sac tumors.

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“…Diffusion-weighted imaging (DWI) is reportedly helpful in differentiating germinoma germ cell tumors from YSTs. YSTs show facilitated diffusion with a high apparent diffusion coefficient value ( 8 ). The value of DWI and other functional MRI studies in the diagnosis of YSTs requires further study.…”

Section: Discussionmentioning

confidence: 99%

Intracranial pure yolk sac tumor in the anterior third ventricle of an adult: A case report

Zhao

Shao

Guo

et al. 2014

Experimental and Therapeutic Medicine

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A 45-year-old female patient presented with symptoms of polydipsia and polyuria, menopause, headache, gait disturbance and deteriorated mental state. Brain magnetic resonance imaging (MRI) showed an irregular mass in the anterior third ventricle. The tumor was excised using a transfrontal approach from the anterior section of the third ventricle. The histological diagnosis was of an intracranial pure yolk sac tumor. The patient underwent radiotherapy and suffered no tumor recurrence one year after the surgery. Overall, when heterogeneous enhancement and an irregular mass with surrounding invasion and ventricular dilation are observed in the anterior third ventricle of an adult, a yolk sac tumor should be considered, and MRI may aid the differential diagnosis. A combination of surgical resection and radiotherapy is recommended for the yolk sac tumor.

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Intracranial yolk sac tumor in an adult patient: MRI, diffusion-weighted imaging and 1H MR spectroscopy features

Cited by 10 publications

References 21 publications

Mixed Germ Cell Tumor with a Yolk Sac Tumor Component in the Medulla Oblongata of a 50-year-old Patient: A Case Report and Literature Review

Mixed Germ Cell Tumor with a Yolk Sac Tumor Component in the Medulla Oblongata of a 50-year-old Patient: A Case Report and Literature Review

Multifocal primary intracranial yolk sac tumor in an adult patient: a case report and literature review

Intracranial pure yolk sac tumor in the anterior third ventricle of an adult: A case report

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