Intracytoplasmic sperm injection: achievement of high pregnancy rates in couples with severe male factor infertility is dependent primarily upon female and not male factors

Oehninger, Sergio; Veeck, Lucinda L.; Lanzendorf, Susan E.; Maloney, Mary; Toner, James P.; Muasher, Suheil J.

doi:10.1016/s0015-0282(16)57913-8

Cited by 147 publications

(110 citation statements)

References 14 publications

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“…come of ICSI provided sperm viability is documented (4,5). Indeed we reported recently that the pregnancy rate from ICSI with spermatozoa recovered through percutaneous epididymal sperm aspiration (PESA) is similar to that following the use of ejaculated sperm (3,6).…”

mentioning

confidence: 99%

Embryo developmental stage at transfer influences outcome of treatment with intracytoplasmic sperm injection

Zhu

Meniru

Craft

1997

J Assist Reprod Genet

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mentioning

confidence: 99%

Embryo developmental stage at transfer influences outcome of treatment with intracytoplasmic sperm injection

Zhu

Meniru

Craft

1997

J Assist Reprod Genet

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“…Beyond the male factor, the efficacy of all assisted reproductive technique is directly correlated with female age with a significant pregnancy expectancy over 40 years old (Oehninger et al 1995;Devroey et al 1996).…”

Section: Ivf and Icsi Resultsmentioning

confidence: 99%

Effectiveness of Assisted Reproduction Techniques as an Answer to Male Infertility

Chamayou¹,

Guglielmino²

2012

Male Infertility

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“…In fact, other studies comparing embryos obtained through classical IVF or ICSI with sperm from severe male infertility showed that they had potential similar developmental viabilities, 26,27 and pregnancy, miscarriage and live birth rates are similar after adjustment for maternal factors. 9,21 A similar study comparing male and tubal factors showed that male factor infertility was related to lower pregnancy rate and a trend toward lower live birth rate. 28 Concerning perinatal outcomes, ICSI for male factor infertility was also not associated with changes in length of gestation, baby birth weight, sex ratio, rate of pregnancy loss and congenital malformations in other reports.…”

Section: Discussionmentioning

confidence: 97%

“…Adequate female age is a pivotal factor determining successful outcomes, even when severe male factor is the main fertility cause. 21 In our study, we subdivided our sample into two age groups, younger women (≤ 35 years old) and older women (> 35 years old), to reduce the bias of maternal age on outcomes. In younger women, we observed a higher fertilization rate in the tubal factor group and a higher number of transferred embryos in the male factor group, but these differences did not impact the implantation rate and subsequent pregnancy rate, which were similar between infertility groups.…”

Section: Discussionmentioning

confidence: 99%

Overcoming male factor infertility with intracytoplasmic sperm injection

Borges

Zanetti

Braga

et al. 2017

Rev. Assoc. Med. Bras.

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Objective:To evaluate the effect of male factor infertility on intracytoplasmic sperm injection (ICSI) outcomes compared with a control group presenting isolated tubal factor. Method: This retrospective study included 743 couples undergoing ICSI as a result of isolated male factor and a control group consisting of 179 couples undergoing ICSI as a result of isolated tubal factor, performed in a private university--affiliated in vitro fertilization center, between January/2010 and December/2016. Patients were divided into two groups according to maternal age: women ≤35 years old and >35 years old. The effects of infertility causes on laboratorial and clinical ICSI outcomes were evaluated using Student's t-test and χ 2 test. Results: No differences in controlled ovarian stimulation outcomes were observed between male factor cycles and tubal factor cycles in the two age groups. Implantation (male factor 35.5% vs. tubal factor 32.0%, p=0.340), pregnancy (male factor 46.9% vs. tubal factor 40.9%, p=0.184) and miscarriage (male factor 10.3% vs. tubal factor 10.6%, p=0.572) rates were similar between the infertility groups, irrespective of female age. Considering maternal age, the cancelation rate was higher in older women (>35 years old) undergoing ICSI as a result of male factor infertility (17.4% vs. 8.9%, p=0.013). Conclusion: Our results showed that there is no difference in the outcomes of pregnancy between couples with male or tubal factor infertility, which indicates that ICSI surpasses the worse specific outcomes associated with male factor.

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Intracytoplasmic sperm injection: achievement of high pregnancy rates in couples with severe male factor infertility is dependent primarily upon female and not male factors

Cited by 147 publications

References 14 publications

Embryo developmental stage at transfer influences outcome of treatment with intracytoplasmic sperm injection

Embryo developmental stage at transfer influences outcome of treatment with intracytoplasmic sperm injection

Effectiveness of Assisted Reproduction Techniques as an Answer to Male Infertility

Overcoming male factor infertility with intracytoplasmic sperm injection

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