Intralesional steroid injection alleviates nail lichen planus

Brauns, Birka; Stahl, Maren; Schön, Michael P.; Zutt, Markus

doi:10.1111/j.1365-4632.2010.04786.x

Cited by 13 publications

(6 citation statements)

References 6 publications

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“…Oral prednisone 0.5 mg/kg for 3 weeks demonstrated a marked improvement and is useful when multiple nails are affected. 150,151 Topical steroids applied to the involved sites, especially in occlusive dressing, appear to have good results in some patients.…”

Section: Nail Lichen Planusmentioning

confidence: 99%

See 1 more Smart Citation

European S1 guidelines on the management of lichen planus: a cooperation of the European Dermatology Forum with the European Academy of Dermatology and Venereology

Ioannides

Vakirlis

Kemény

et al. 2020

Acad Dermatol Venereol

117

151

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Lichen planus (LP) is a chronic inflammatory and immune-mediated disease that affects the skin, hair, nails and mucous membranes. Although there is a broad clinical spectrum of lichen planus manifestations, the skin and oral cavity remain the major sites of involvement. A group of European dermatologists with a long-standing interest and expertise in lichen planus has sought to define therapeutic guidelines for the management of patients with LP. The clinical features, diagnosis and possible medications that clinicians can use, in order to control the disease, will be reviewed in this manuscript.The revised final version of the lichen planus guideline was passed on to the European Dermatology Forum (EDF) for a final consensus with the European Academy of Dermatology and Venereology (EADV).

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Section: Nail Lichen Planusmentioning

confidence: 99%

“…The following treatment modalities (Table 13) can be considered as an alternative therapy to steroids. 151,152 Other forms of LP The treatment of other forms of LP is symptomatic and depends on the location of that lichenoid reaction on skin or mucosal according to the above suggestions.…”

Section: Nail Lichen Planusmentioning

confidence: 99%

European S1 guidelines on the management of lichen planus: a cooperation of the European Dermatology Forum with the European Academy of Dermatology and Venereology

Ioannides

Vakirlis

Kemény

et al. 2020

Acad Dermatol Venereol

117

151

View full text Add to dashboard Cite

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“…Conservative first-line therapies include superpotent TCS, often under occlusion, but these are usually unsuccessful. Intralesional steroids are more effective; a single injection of triamcinolone acetonide 10 mg/ml into the proximal nail fold yielded complete recovery within several months and lasted 2 years in one patient (Brauns et al, 2011). Alternatively, systemic steroid therapy with oral prednisone or intramuscular injection of triamcinolone acetonide has provided better outcomes.…”

Section: Introductionmentioning

confidence: 99%

“…Alternatively, systemic steroid therapy with oral prednisone or intramuscular injection of triamcinolone acetonide has provided better outcomes. Unfortunately, recurrence has been reported with all therapies for nail LP (Brauns et al, 2011). …”

Section: Introductionmentioning

confidence: 99%

Update on lichen planus and its clinical variants

Weston

Payette

2015

International Journal of Women's Dermatology

181

179

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Lichen planus (LP) is an inflammatory skin condition with characteristic clinical and histopathological findings. Classic LP typically presents as pruritic, polygonal, violaceous flat-topped papules and plaques; many variants in morphology and location also exist, including oral, nail, linear, annular, atrophic, hypertrophic, inverse, eruptive, bullous, ulcerative, lichen planus pigmentosus, lichen planopilaris, vulvovaginal, actinic, lichen planus-lupus erythematosus overlap syndrome, and lichen planus pemphigoides. Clinical presentation of the rarer variant lesions may be largely dissimilar to classic LP and therefore difficult to diagnose based solely on clinical examination. However, histopathological examination of LP and LP-variant lesions reveal similar features, aiding in the proper diagnosis of the disease. Management of LP and LP variants aims to control symptoms and to decrease time from onset to resolution; it often involves topical corticosteroids, but varies depending on the severity and location of the lesion. The literature contains an array of reports on the variations in presentation and successful management of LP and its variants. A familiarity with LP and its variants is important in achieving timely recognition and management of the disease.

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“…While some of these agents may be appropriate for use in ocular, oral, and genital mucosae, other formulations (e.g., dexamethasone solution for management of the oral mucosa), including utilization of compounding, can be highly effective (Carpenter et al, ; Lutz & Mielke, ; Mawardi, Stevenson, Gokani, Soiffer, & Treister, ). Patients with localized yet severe oral, cutaneous, or genital lesions may benefit significantly from intralesional corticosteroid therapy with the advantage of delivering a higher concentration of drug locally with less risk of systematic toxicity (Amirnia et al, ; Brauns, Stahl, Schon, & Zutt, ; Treister et al, ; Zegarelli, ). In general, ancillary therapies should be maximized to reduce the need for systemic immunosuppression.…”

Section: Management Of Cgvhdmentioning

confidence: 99%

Chronic graft‐versus‐host disease: Current management paradigm and future perspectives

et al. 2018

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Chronic GVHD is a serious disease which may be active for years, or even decades, requiring potentially years of immunosuppressive therapies and placing patients at risk for a number of late complications. While the oral cavity has long been recognized to be a prominent target of GVHD, and in particular, chronic GVHD, it must be recognized and appreciated that it is a complex systemic disease with a wide spectrum of clinical manifestations.

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Intralesional steroid injection alleviates nail lichen planus

Cited by 13 publications

References 6 publications

European S1 guidelines on the management of lichen planus: a cooperation of the European Dermatology Forum with the European Academy of Dermatology and Venereology

European S1 guidelines on the management of lichen planus: a cooperation of the European Dermatology Forum with the European Academy of Dermatology and Venereology

Update on lichen planus and its clinical variants

Chronic graft‐versus‐host disease: Current management paradigm and future perspectives

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