Intraocular pressure more reduced during anesthesia with propofol than with sevoflurane: both combined with remifentanil

Schäfer, Ralph; Klett, J; Auffarth, Gerd U.; Polarz, H.; Völcker, Hans-Eberhard; Martín, E; Böttiger, B. W.

doi:10.1034/j.1399-6576.2002.460612.x

Cited by 67 publications

(62 citation statements)

References 14 publications

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“…Anesthetics may reduce IOP via central effects within the diencephalon and by relaxation of the extraocular muscles resulting in improved aqueous humor outflow [17,18] . In human subjects, it was described that propofol decreases IOP equally to inhalation anesthetics [20,21] or that propofol has a stronger IOP-reducing effect than inhalation anesthetics [22,23] . The anesthetics used are known to have vasodilatory effects; the more pronounced effect of propofol on blood pressure might result in part from the negative inotropic effect of propofol [19] and from the inhibition of the release of vasopressin (which induces an increase in IOP [24] ) from the supraoptic nucleus that is caused by propofol but not by inhalation anesthetics [25,26] .…”

Section: Discussionmentioning

confidence: 99%

Effects of Propofol and Isoflurane Anesthesia on the Intraocular Pressure and Hemodynamics of Pigs

Buehner

Pietsch²,

Bringmann³

et al. 2010

Ophthalmic Res

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To determine the conditions under which anesthetized pigs can be used in acute noninvasive investigations of ocular hydro- and hemodynamics, the intraocular pressure (IOP) of adult pigs was recorded under the following conditions: (1) after intravenous injection of propofol plus ketamine; (2) during inhalation of isoflurane, and (3) 2 h after topical administration of bimatoprost or (4) timolol. Propofol/ketamine and isoflurane induced significant decreases in the IOP. The pulsation of the ophthalmic artery appeared at a significantly higher IOP in animals anesthetized with isoflurane than in those anesthetized with propofol/ketamine. Bimatoprost and timolol did not significantly decrease the IOP within 2 h after topical administration. It is concluded that different techniques for the acute noninvasive investigation of ocular hydro- and hemodynamics are applicable in anesthetized pigs. To test the effects of antiglaucoma agents, investigation periods longer than 2 h are required. We recommend the use of intravenous propofol/ketamine anesthesia rather than isoflurane anesthesia in future experiments using pigs.

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Section: Discussionmentioning

confidence: 99%

Effects of Propofol and Isoflurane Anesthesia on the Intraocular Pressure and Hemodynamics of Pigs

Buehner

Pietsch²,

Bringmann³

et al. 2010

Ophthalmic Res

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“…However, IOP increased at 3 hours after induction of anesthesia compared with starting point in both patients with and without N 2 O. Intraocular pressure (IOP) is known to changing at perioperative period due to anesthetic maneuvers [3] [17], anesthetic agents [4] [18]- [21], and patient's position [22]- [27] and hemodynamics [28]. Tracheal intubation [29], succinylcholine [5]- [7], inhalational anesthesia [1] [2] [8], and nitrous oxide (N 2 O) [21] may influence IOP. Inhalational anesthetics and propofol have been shown to decrease IOP [8], whereas succinylcholine can increase IOP [5]- [7].…”

Section: Discussionmentioning

confidence: 99%

“…Tracheal intubation [29], succinylcholine [5]- [7], inhalational anesthesia [1] [2] [8], and nitrous oxide (N 2 O) [21] may influence IOP. Inhalational anesthetics and propofol have been shown to decrease IOP [8], whereas succinylcholine can increase IOP [5]- [7]. Previous studies demonstrated that general anesthesia with halothane, enflurane, propofol, and fentanyl would decrease IOP after tracheal intubation [2]- [5].…”

Section: Discussionmentioning

confidence: 99%

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The Effect of Nitrous Oxide on the Intraocular Pressure in Patients Undergoing Abdominal Surgery under Sevoflurane and Remifentanil Anesthesia

Goyagi¹,

Sato²,

Horiguchi³

et al. 2016

OJAnes

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Introduction: Although inhalational anesthesia and nitrousoxide (N 2 O) are known to affect the intraocular pressure (IOP), little is known about the effect of nitrousoxide on the IOP during sevoflurane and remifentanil anesthesia. In the present study, we examined the effect of balanced anesthesia on the IOP. Materials and Methods: After obtaining informed consent, the patients undergoing abdominal surgery under general anesthesia were divided into two groups: N 2 O group (n = 10) and control group (n = 12). General anesthesia was maintained with remifentanil (0.05 -0.3 µg/kg/min), 33% O 2 and 1.2% sevoflurane to keep ETCO 2 of 35 -40 mmHg following tracheal intubation. After baseline measurement of IOP (T0, 20 minutes after injection of anesthesia), the patients in the N 2 O group received 67% nitrousoxide, and the patients in the control group received air, with O 2 and 1.2% sevoflurane. Then, IOP was measured at 1 hour (T1), 2 hours (T2), and 3 hours (T3) after anesthesia induction in the supineposition. Blood pressure and heart rate were recorded at the same time interval. Results: There was no significant difference in the IOP at any period between the two groups. In both groups, the IOP at the T3 was significantly higher than that at T0. Conclusion: These results suggest that N 2 O does not affect the IOP in patients undergoing abdominal surgery under sevoflurane and remifentanil anesthesia.

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“…Propofolun göz içi basıncını düşürmedeki etkinliği iyi bilinmektedir (36). Antiemetik özelliği nedeniyle de şaşılık cerrahisinde tercih nedeni olmuştur.…”

Section: Oftalmik Cerrahide Genel Anesteziunclassified

Oftalmik cerrahide anestezi

Bor¹,

Certug²

2015

Ege Tıp Dergisi

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ÖzAnestezistler için oküler cerrahide birçok uygun anestezi tekniği mevcuttur. Günümüzde genel anestezi yöntemi bilinen temel ilaçları içermesine rağmen (intravenöz anestezikler ve inhalasyon anestezikleri, opiyoidler ve kas gevşeticiler) göz cerrahisinde daha az sıklıkla uygulanan anestezi yöntemidir. Genel anestezi; mental retarde, uyum sağlamada güçlüğü olan, yaşlı ve çocuk hastalar ile lokal anesteziyi reddeden hastalara uygulanmaktadır. Rejyonel veya genel anestezi yöntemi anestezistin deneyimine bağlıdır. Göz cerrahisi hasta grubunda artan yaş ve komorbitide, her tekniğin dikkatli yönetimini ve cerrah ile anestezistin iyi bir iletişimini gerektirir. Göz cerrahisinde uygulanan anestezi yöntemi ve yönetimi cerrahinin güvenliği ve başarısında kritik rol oynar.Anahtar Sözcükler: Oftalmik anestezi. Abstract Many anesthetic techniques are available in ocular surgery for the anestesiologists.Currently general anesthesia includes basic products (intravenous and inhalation anesthetics, opioids, and neuromuscular blockers) but less utilised in ophthalmology. General anaesthesia is indicated in debile, uncooperative or senile patients, in patients who refuse loco-regional procedures and in children. Regional or general anesthetic methods depends on the experience of the anesthetist. Increasing aging and comorbidity in the ophthalmic patient population needs careful management of each technique and therefore sufficient communication between anaesthesiologist and surgeon is essential.Ocular anesthetic techniques and managements play a critical role for the success and safety of ophthalmic surgery.

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Intraocular pressure more reduced during anesthesia with propofol than with sevoflurane: both combined with remifentanil

Cited by 67 publications

References 14 publications

Effects of Propofol and Isoflurane Anesthesia on the Intraocular Pressure and Hemodynamics of Pigs

Effects of Propofol and Isoflurane Anesthesia on the Intraocular Pressure and Hemodynamics of Pigs

The Effect of Nitrous Oxide on the Intraocular Pressure in Patients Undergoing Abdominal Surgery under Sevoflurane and Remifentanil Anesthesia

Oftalmik cerrahide anestezi

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