Intraoperative Fluorescence Imaging System for On-Site Assessment of Off-Pump Coronary Artery Bypass Graft

Waseda, Katsuhisa; Ako, Junya; Hasegawa, Takao; Shimada, Yoshihisa; Ikeno, Fumiaki; Ishikawa, Toshihiro; Demura, Yoshitaka; Hatada, Kazuyoshi; Yock, Paul G.; Honda, Yasuhiro; Fitzgerald, Peter J.; Takahashi, Masao

doi:10.1016/j.jcmg.2008.12.028

Cited by 54 publications

(30 citation statements)

References 21 publications

(18 reference statements)

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“…Waseda and colleagues also had same experience as ours. 12 Further analysis may be necessary to clarify the clinical implications of this IFI finding.…”

Section: Discussionmentioning

confidence: 93%

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Intraoperative Validation of Left Internal Mammary Artery Graft by Flourescence Imaging Technique

et al. 2018

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Background: In coronary artery bypass surgery (CABG) left internal mammary artery (LIMA) is considered gold standard conduit of choice for myocardial revascularization. Graft failure following CABG reduces cardiac mortality and morbidity both in short and long term. Although conventional angiography is gold standard for assessing graft patency but rarely available in same operating room. So intraoperative florescence imaging could be an efficient and reliable method of assessing the patency of graft.Methods: This study was conducted between July 2013 to June 2014 in the Department of Cardiac Surgery of National Institute of Cardiovascular Diseases (NICVD). Thirty six LIMA grafts were assessed by using IFI system .ICG administered through CVP line and imaging acquired during pass of the ICG through field of view graft flow. Quality of anastomosis was intra operatively to validate graft.Results: Mean age of study population was 54±8.38 years. Per operative assessment of LIMA to left anterior descending artery revealed 32 (88.8%) patent anastomosis, narrowing of anastomosis was found in 2 (5.55% ) patients.Conclusion: Intraoperative fluorescence imaging is an effective and inexpensive way to validate patency of LIMA graft.Cardiovasc. j. 2018; 10(2): 145-149

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“…Waseda and colleagues also had same experience as ours. 12 Further analysis may be necessary to clarify the clinical implications of this IFI finding.…”

Section: Discussionmentioning

confidence: 93%

“…These results are almost identical to those of other groups (approximately 5%) who have used this technology. 12 In all cases, the lesions would have otherwise been missed by the operating room team. The clinical consequences of early graft failure are not benign.…”

Section: Discussionmentioning

confidence: 99%

Intraoperative Validation of Left Internal Mammary Artery Graft by Flourescence Imaging Technique

et al. 2018

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“…Likewise, ICG-AG has been commonly used for evaluating graft patency. Many reports in literature demonstrated the effectiveness of ICG-AG for CABG [1][2][3][4][5]. In Japan, the SPY system and HEMS have been used for CABG; however, quantitative analysis has not been a popular method because a better analysis software program is not yet available.…”

Section: Discussionmentioning

confidence: 99%

“…Indocyanine green angiography (ICG-AG) is used to assess grafts for coronary artery bypass grafting (CABG) [1][2][3][4]. Previously, we developed a prototype color ICG-AG system, the HyperEye Medical System (HEMS; Mizuho IKAKOGYO Inc., Tokyo, Japan), and have used it with TTFM (VeriQ; Medistim, Oslo, Norway) for intraoperative graft evaluation since 2007 [5,6].…”

Section: Introductionmentioning

confidence: 99%

New Quantitative Analysis Method Using HyperEye Medical System Image for Coronary Artery Bypass Grafting

Takemi¹,

Orihashi²,

Nishimori³

et al. 2017

Angiol

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Purpose: The current evaluation by indocyanine green angiography in coronary artery bypass patients has been performed by qualitative analysis. We devised an original quantitative analysis method using Image J.Methods: Indocyanine green angiography movie was converted to spatiotemporal images. Using the spatiotemporal image, an indocyanine green fluorescence intensity curve was drawn and converted to a firstderivative (acceleration) curve. Indocyanine green angiography evaluations were classified into four types. We collected the peak indocyanine green fluorescence intensity value (peak-I) and both time interval and ratio of maximum indocyanine green acceleration value (max dI/dt) between the mid and distal portions of the graft. Results:In 61 left internal thoracic artery grafts, 49 were patent and 12 were abnormal on CAG. There were significant differences between peak-I at the mid portion of the graft (221.47 ± 39.33 vs. 184.82 ± 40.15 gray scale) and time delay with max dI/dt (0.45 ± 1.28 vs. −1.00 ± 1.25 s), but there was no significant difference in the ratio of max dI/dt between patent and abnormal grafts. Conclusions:The spatiotemporal image method may become a model of the analysis software and the time interval of max dI/dt may become a predictor for future graft failure.

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“…Следует также отметить, что приме-нявшаяся нами для ангиографии система SPY («Novadaq Technologies Inc.», Канада) позволяет проводить визуаль-ную оценку состояния шунтов и КА на участке, площадью 7,5×7,5 см. В ряде случаев исследуемый шунт может ча-стично находиться за пределами зоны захвата изображе-ния, что не позволяет оценить характер распределения контраста в шунте на всем протяжении [8]. Однако даль-нейшее совершенствование аппаратных средств для вы-полнения ИЦЗ позволит расширить возможности метода.…”

Section: рис 2 окклюзия бранши композитного п-шунтаunclassified

Intraoperative indocyanine green angiography as a method assessing immediate results of coronary artery bypass grafting: possibilities and prospects of use

Семченко¹,

Andreev²,

Yavnyi³

et al. 2015

Kardiol. serdechno-sosud. khir.

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Ключевые слова: прямая реваскуляризация миокарда, ангиография с индоцианином зеленым.An experience of intraoperative qualitative assessment of the results of coronary artery bypass grafting using indocyanine green angiography is presented. The study included 34 patients with coronary artery disease (age 63±7.7 years). It was studied the patency of 96 coronary bypass grafts. The advantages, disadvantages and possibilities of indocyanine green angiography for assessment of blood flow in coronary bypass grafts were established. We revealed that intraoperative imaging technique with qualitative assessment of blood flow in coronary bypass grafts using indocyanine green angiography is safe, simple, reproducible and informative procedure.Keywords: direct myocardial revascularization, indocyanine green angiography.

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Intraoperative Fluorescence Imaging System for On-Site Assessment of Off-Pump Coronary Artery Bypass Graft

Abstract: The IFI system enables on-site assessment of graft patency, providing both morphologic and functional information. This technique may help reduce procedure-related, early graft failures in off-pump bypass patients.

Cited by 54 publications

References 21 publications

Intraoperative Validation of Left Internal Mammary Artery Graft by Flourescence Imaging Technique

Intraoperative Validation of Left Internal Mammary Artery Graft by Flourescence Imaging Technique

New Quantitative Analysis Method Using HyperEye Medical System Image for Coronary Artery Bypass Grafting

Intraoperative indocyanine green angiography as a method assessing immediate results of coronary artery bypass grafting: possibilities and prospects of use

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