Intraoperative magnetic resonance imaging in the surgical treatment of cerebral metastases

Senft, Christian; Seifert, Volker; Gasser, Thomas

doi:10.1002/jso.21508

Cited by 29 publications

(16 citation statements)

References 49 publications

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“…Advances in surgical techniques have been studied in an attempt to optimize local tumor control in patients with single brain metastases undergoing resection. Techniques such as microsurgical resection and intraoperative MRI have been used in attempts to improve the success of surgical resection for brain metastases, but are not yet the standard of care [10,11]. …”

Section: Surgerymentioning

confidence: 99%

Treatment of Brain Metastases

Lukas¹,

Gabikian²,

Garza³

et al. 2014

Oncology

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Brain metastases are associated with substantial morbidity and mortality. Key prognostic classification systems for brain metastases are reviewed. The role of surgery, particularly for single brain metastases, is discussed. This is followed by an overview of radiation, both whole brain and focal, in the treatment of brain metastases. Finally, we review examples of important concepts regarding the role of systemic therapy in the treatment of brain metastases.

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Section: Surgerymentioning

confidence: 99%

Treatment of Brain Metastases

Lukas¹,

Gabikian²,

Garza³

et al. 2014

Oncology

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“…oncology. [1][2][3][4][5] These have in common that the target area is relatively rigid due to surrounding bony structures. Part of the pelvic structures, such as pelvic muscles, sacral nerves, ureters, and iliac vessels are also reasonably rigid with respect to the pelvic bony structures.…”

mentioning

confidence: 99%

Prospective study on image‐guided navigation surgery for pelvic malignancies

Nijkamp

Kuhlmann

Ivashchenko

et al. 2018

Journal of Surgical Oncology

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Background and objectives Surgery of advanced tumors and lymph nodes in the pelvis can be challenging due to the narrow pelvic space and vital surrounding structures. This study explores the application of a novel electromagnetic navigation system to guide pelvic surgery. Methods This was a prospective study on surgery for malignancies in the pelvis. Preoperatively obtained imaging was used to create a patient‐specific three‐dimensional (3D) roadmap. In the operating room, the 3D roadmap was registered to an intraoperative computed tomography scan. A tracked pointer was used during surgery for guidance. Primary endpoint was safety and feasibility, secondary endpoints were accuracy and usability. Results Twenty‐eight colorectal, four liposarcomas, and one gynecological patient were included. There were no safety issues. Navigation was feasible in 31 patients. The mean target registration errors of 4.0 and 6.3 mm were achieved for straight and French position, respectively. In seven of seven patients with a locally advanced rectal tumor and in seven of eight patients with recurrences, negative margins were achieved. Thirty‐three of 36 target lymph nodes were successfully removed. Surgeons using the system indicated faster localization of the tumor and improved decisiveness. Conclusion This novel surgical navigation system was safe and feasible during pelvic surgery and can facilitate its users.

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“…The application of this system in cranial neurosurgery and its clinical usefulness have been described extensively. 12,13 Anesthesia and Monitoring Induction of anesthesia was performed using fentanyl (2 mg/kg), propofol (2 mg/kg), and rocuronium (0.5 mg/kg). Anesthesia was kept up during surgery with continuous infusion of remifentanil (0.1 to 0.2 mg/kg/min) and propofol (6 mg/kg/h).…”

Section: Materials and Methods Imri Systemmentioning

confidence: 99%