Intraperitoneal nebulization of ropivacaine for pain control after laparoscopic cholecystectomy: a double-blind, randomized, placebo-controlled trial

Ingelmo, Pablo; Bucciero, Mario; Somaini, Marta; Sahillioğlu, Emre; Garbagnati, Andrea; Charton, Antoine; Rossini, Valeria; Sacchi, V.; Scardilli, Marcella; Lometti, A.; Joshi, Girish P.; Fumagalli, Roberto; Diemunsch, Pierre

doi:10.1093/bja/aes495

Cited by 63 publications

(49 citation statements)

References 16 publications

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“…Therefore, irritation of the diaphragm or stimulation of sensory fibers in the phrenic nerve can be experienced as referred pain in the shoulder area, due to the embryological origins of the www.journals.viamedica.pl diaphragm. After gynaecological laparoscopy, shoulder tip pain is induced by stretching of the diaphragm on insufflation of carbon dioxide to maintain the pneumoperitoneum [16]. Women with a ruptured ectopic pregnancy may develop shoulder pain on depressing the head of the bed, presumably due to irritation of the diaphragm by blood and fluid [17].…”

Section: Embryology Of the Diaphragmmentioning

confidence: 99%

Network of Breathing. Multifunctional Role of the Diaphragm: A Review

Kocjan

Adamek

Gzik-Zroska

et al. 2017

Advances in Respiratory Medicine

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The diaphragm is the primary muscle involved in active inspiration and serves also as an important anatomical landmark that separates the thoracic and abdominal cavity. However, the diaphragm muscle like other structures and organs in the human body has more than one function, and displays many anatomic links throughout the body, thereby forming a 'network of breathing'. Besides respiratory function, it is important for postural control as it stabilises the lumbar spine during loading tasks. It also plays a vital role in the vascular and lymphatic systems, as well as, is greatly involved in gastroesophageal functions such as swallowing, vomiting, and contributing to the gastroesophageal reflux barrier. In this paper we set out in detail the anatomy and embryology of the diaphragm and attempt to show it serves as both: an important exchange point of information, originating in different areas of the body, and a source of information in itself. The study also discusses all of its functions related to breathing.

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Section: Embryology Of the Diaphragmmentioning

confidence: 99%

Network of Breathing. Multifunctional Role of the Diaphragm: A Review

Kocjan

Adamek

Gzik-Zroska

et al. 2017

Advances in Respiratory Medicine

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“…Multimodal analgesia has been used to minimize post-VC pain, including the perioperative use of non-steroid anti-inflammatory drugs (NSAIDs), opioids, N-methyl D-aspartate receptor inhibitors (NMDA), anticonvulsants and local anesthetic infiltration in the surgical wound. In this context, intraperitoneal ropivacaine instillation has been suggested by some authors as a feasible and easy resource to control postvideolaparoscopic cholecystectomy pain [6][7][8][9] . This study aimed at evaluating postoperative analgesia with intraperitoneal ropivacaine instillation for VC.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of postoperative analgesia with intraperitoneal ropivacaine instillation in videolaparoscopic cholecystectomy

Albuquerque¹,

Bezerra²,

Schots³

et al. 2016

Revista Dor

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“…Ingelmo et al, showed that Ropivacaine (1%) intraperitoneal nebulisation before and after (3ml) surgery reduced post-operative pain after laparoscopic cholecystectomy. It also reduced Morphine consumption and allowed early mobility [15].…”

Section: Discussionmentioning

confidence: 99%

Pain Management after Laparoscopic Cholecystectomy-A Randomized Prospective Trial of Low Pressure and Standard Pressure Pneumoperitoneum

Singla

Mittal

Raghav

et al. 2014

JCDR

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Background: Abdominal pain and shoulder tip pain after laparoscopic cholecystectomy are distressing for the patient. Various causes of this pain are peritoneal stretching and diaphragmatic irritation by high intra-abdominal pressure caused by pneumoperitoneum . We designed a study to compare the post operative pain after laparoscopic cholecystectomy at low pressure (7-8 mm of Hg) and standard pressure technique (12-14 mm of Hg).

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Intraperitoneal nebulization of ropivacaine for pain control after laparoscopic cholecystectomy: a double-blind, randomized, placebo-controlled trial

Abstract: Ropivacaine nebulization before or after surgery reduced postoperative pain and referred shoulder pain after laparoscopic cholecystectomy. Furthermore, ropivacaine nebulization reduced morphine requirements and allowed earlier mobility.

Cited by 63 publications

References 16 publications

Network of Breathing. Multifunctional Role of the Diaphragm: A Review

Network of Breathing. Multifunctional Role of the Diaphragm: A Review

Evaluation of postoperative analgesia with intraperitoneal ropivacaine instillation in videolaparoscopic cholecystectomy

Pain Management after Laparoscopic Cholecystectomy-A Randomized Prospective Trial of Low Pressure and Standard Pressure Pneumoperitoneum

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