Intrathoracic Thyroid Solitary Fibrous Tumor Presenting with Respiratory Failure

Lin, Mong-Wei; Wu, Chen-Tu; Lee, Yi‐Hsuan; Chang, Yih‐Leong

doi:10.5761/atcs.cr.12.02068

Cited by 4 publications

(3 citation statements)

References 13 publications

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“…Rarely, the tumor may extend inferiorly from the thyroid gland and present as a mediastinal goiter/mass [30,37]. While most patients are asymptomatic, uncommonly the tumor can compress the adjacent esophagus or trachea resulting in dyspnea, dysphagia, or hoarseness [27,30,33,[35][36][37][38]. Patients are euthyroid, with thyroid function tests within normal limits [20,21,24,25,29,[31][32][33][34][35][36][37][38].…”

Section: Discussionmentioning

confidence: 99%

“…While most patients are asymptomatic, uncommonly the tumor can compress the adjacent esophagus or trachea resulting in dyspnea, dysphagia, or hoarseness [27,30,33,[35][36][37][38]. Patients are euthyroid, with thyroid function tests within normal limits [20,21,24,25,29,[31][32][33][34][35][36][37][38]. Preoperative diagnosis of solitary fibrous tumor affecting the thyroid gland by fine needle aspiration is exceedingly difficult, as aspirates are generally non diagnostic due to low cellularity [17,25,27,28,31,32,38].…”

Section: Discussionmentioning

confidence: 99%

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Thyroid Gland Solitary Fibrous Tumor: Report of 3 Cases and a Comprehensive Review of the Literature

Thompson

Wei

Rooper

et al. 2019

Head and Neck Pathol

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Solitary fibrous tumors of the thyroid gland are exceptionally rare. In order to further characterize the clinical and pathologic features of solitary fibrous tumor arising at this anatomic site, three cases of thyroid gland solitary fibrous tumor were analyzed in conjunction with 35 cases compiled from the English literature. Thyroid gland solitary fibrous tumors showed an equal sex distribution with a mean age at presentation of 54.4 years (range, 28-88 years). The patients typically presented with an asymptomatic, slow growing neck mass. Microscopically, the tumors were characterized by cytologically bland spindle cells with patternless growth, hypocellular and hypercellular areas, variable amounts of collagen, and ectatic, branching blood vessels. Two previous reported tumors were considered to be histologically malignant on the basis of increased mitotic activity, profound pleomorphism and tumor necrosis. Immunohistochemically, the tumor cells are variably positive with CD34, bcl-2, and CD99. STAT6 immunohistochemistry, performed on the current cases, demonstrated a strong, diffuse nuclear expression in all tumors. Among 26 patients with available follow up data (mean 47.3 months), one developed local recurrence and distant metastasis. Solitary fibrous tumors occurring in the thyroid gland are uncommon, but can be reliably diagnosed based on the presence of characteristic morphologic features as well as immunohistochemical expression of STAT6 and CD34. The majority of thyroid gland solitary fibrous tumors have exhibited an indolent clinical course, however experience is limited. The rare potential for aggressive clinical behavior requires clinical surveillance.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Thyroid Gland Solitary Fibrous Tumor: Report of 3 Cases and a Comprehensive Review of the Literature

Thompson

Wei

Rooper

et al. 2019

Head and Neck Pathol

View full text Add to dashboard Cite

show abstract

“…Con los datos disponibles, el TFST tiene una edad media de presentación de 58 años (rango 28-88 años), sin diferencia de género, y con tamaño variable entre 17 y 150 mm; siendo este caso el tumor de mayor tamaño reportado. Se localizan con igual frecuencia en ambos lóbulos y puede tener extensión intratorácica 17,22 , como se ha reportado en dos casos más. La clínica es similar a la reportada por otras neoplasias tiroideas, masa cervical firme, de crecimiento progresivo, en ocasiones significativo, produciendo síntomas como disnea, disfonía y disfagia.…”

Section: Discussionunclassified

Tumor fibroso solitario de la glándula tiroides con extensión intratorácica

et al. 2016

Rev. Otorrinolaringol. Cir. Cabeza Cuello

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Extrapleural solitary fibrous tumor of the thyroid gland: A case report and review of literature

Suh¹,

Park²,

Jeon³

et al. 2020

WJCC

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Intrathoracic Thyroid Solitary Fibrous Tumor Presenting with Respiratory Failure

Cited by 4 publications

References 13 publications

Thyroid Gland Solitary Fibrous Tumor: Report of 3 Cases and a Comprehensive Review of the Literature

Thyroid Gland Solitary Fibrous Tumor: Report of 3 Cases and a Comprehensive Review of the Literature

Tumor fibroso solitario de la glándula tiroides con extensión intratorácica

Extrapleural solitary fibrous tumor of the thyroid gland: A case report and review of literature

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