Investigation into antiproliferative activity and apoptosis mechanism of new arene Ru(ii) carbazole-based hydrazone complexes

Abstract

Ruthenium complexes with bioactive ligands become the promising substitutes to platinum complexes by showing their precise actions against various cancers. In the present study, the synthesis of three new...

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“…The reduced cell viability on day 1 was due to the presence of free Ce-nGel with the NIH3T3 fibroblasts. After day 1, the remaining viable fibroblasts multiplied, consequently improving the viability (Subarkhan & Ramesh, Kasim et al, 2018;Mohamed Subarkhan et al, 2019;Balaji et al, 2020;Sathiya Kamatchi et al, 2020).…”

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“…The sterilized swab was immediately placed on wound thus carrying wound exudates along with it and these carried wound exudates were cultured in LB broth. Following dissolution, the broth was incubated at 37 C for 24-48 h. Bacteria were then streaked on LB agar plates separately for determination of shape and biochemical assays including gram staining, catalase, coagulase, and oxidase (Mohan et al, 2018;Sathiya Kamatchi et al, 2020;Sonamuthu et al, 2020). The cultured plates were treated with both bandages, and zones of inhibition were measured to see the antibacterial effect.…”

Self-Assembly by Tridentate or Bidentate Ligand: Synthesis and Vapor Adsorption Properties of Cu(II), Zn(II), Hg(II) and Cd(II) Complexes Derived from a Bis(pyridylhydrazone) Compound

“…Within the field of supramolecular chemistry, hydrazone derivatives have been one of the most important classes of flexible and versatile polydentate ligands which show very high efficiency in chelating with transition metal ions [1][2][3][4][5][6]. The coordinating ability of hydrazones is possible due to the nucleophilic character of the nitrogen atoms of the triatomic structure C=N-N of the azomethine group [7,8]. So far, hydrazone-based metal complexes have received considerable attention from chemists in many applications such as chromogenic reagents in the spectrophotometric determination of transition-metal ions, metal extracts and biologically active compounds [9].…”