Natural gas is a promising alternative fuel for internal combustion engines, it allows for a reduction of engine-out emissions without impairing high engine efficiencies. Although this approach is already utilized from small to large engine classes, it is almost exclusively based on the combustion of a premixed, homogeneous charge. For ignition, small engines use standard spark-plugs or pre-chambers, while large and lean-operated engines use pre-chambers and pilot injections. Direct high-pressure gas injection is a more recent, alternative way to operate gas engines which offers benefits compared to premixed operation such as high compression ratio, high combustion pressures, lean operation, quantity regulation, among others. However, in contrast to diesel direct injection, the compression temperatures are too low for the auto-ignition of the gas jets. Therefore, an additional ignition system is required, usually a pilot injection system is used. In this study, the usability and performance of three ignition strategies for direct injected high-pressure gas jets have been investigated in an optically accessible test-rig that is able to operate at engine-like conditions. The first type of ignition system is a pilot injection with a liquid fuel, the second is a glow-plug located near the main gas jet, and the third system is a pre-chamber with a nozzle hole aimed at the main gas jet. Results show that all three strategies are feasible options under the studied conditions. Ignition by a pilot fuel injection is a safe and reliable way to ignite the main fuel. The glow-plug is less reliable and leads to high cycle-to-cycle variation. The best option in the present study is the pre-chamber, it is very reliable, delivers the highest peak cylinder pressure and exhibits the lowest cyclic variability. The good performance is attributed to the intense mixing of the main gas jet with the hot jet exiting the pre-chamber.