Investigation of C-terminal domain of SARS nucleocapsid protein–Duplex DNA interaction using transistors and binding-site models

Abstract

2016-12-23T18:49:38

SARS-CoV, MERS-CoV and SARS-CoV-2: A Diagnostic Challenge

“…As of December 2019, few groups of unknown patients with pneumonia were affected by a new coronavirus in China [1] . Temporarily, the WHO coined the new coronavirus as 2019 novel coronavirus (2019-nCoV) on January 7, 2020, unexpectedly came into our sight [2] . Later, the virus was consequently renamed SARS-CoV-2.…”

“…In China, previous outbreaks of evolving infectious diseases have negatively affected the blood supply [1] , [2] , [3] . But, the safety of the transfusion recipient must be also taken into account, despite the fact that the evolving infection is a respiratory disease.…”

“…A number of potentially fatal viruses have arose in recently [1] , [2] . In addition to raising major global public health problems, they have been able to cause massive human mortality [3] , [4] .…”

Nanosensor networks for health-care applications

“…Functionalized AlGaN/GaN high electron mobility transistors (HEMTs) have been utilized as an assay for SARS and to examine the binding between double-stranded DNA and the SARS coronavirus nucleocapsid protein [9,10]. These HEMTs have been widely used as biosensors, as summarized in Table 24.1.…”

Label‐Free DNA Sensors Based on Field‐Effect Transistors with Semiconductor of Carbon Materials

“…[92] Existing applications of FET DNA sensor in health care are the detection of gene mutation. [27,88,[93][94][95][96][97] Relying on the developed DNA testing technology based on carbon materials, they can also be used to assist in the detection of other biomolecules. [98,99] Mutual detection of biomolecules is another further trend of biosensors' development.…”