Investigation of the factor in groundnut meal responsible for “turkey X disease”

Iongh, H. de; Beerthuis, R. K.; Vles, R. O.; Barrett, C. B.; Ord, W. O.

doi:10.1016/0006-3002(62)90471-7

Cited by 68 publications

(21 citation statements)

References 2 publications

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“…The aflatoxins were isolated and characterized after the death of more than 100,000 turkey poults ("turkey X disease"), and was traced to the consumption of an Aspergillus-contaminated peanut meal (De Iongh et al 1962). Developing nations, including most of Africa, Latin and South Americas, and Asia are identified as high risk areas for aflatoxin exposure, leading to aflatoxicosis (Williams et al 2004).…”

Section: Aflatoxinsmentioning

confidence: 99%

Dietary mycotoxins, co-exposure, and carcinogenesis in humans: Short review

Ruyck

Boevre

Huybrechts

et al. 2015

Mutation Research/Reviews in Mutation Research

230

148

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Mycotoxins, toxic secondary metabolites of fungi, affect global agriculture so prolifically that they are virtually ubiquitous at some concentration in the average human diet. Studies of in vitro and in vivo toxicity are discussed, leading to investigations of co-exposed mycotoxins, as well as carcinogenic effects. Some of the most common and toxicologically significant mycotoxins, such as the aflatoxins, ochratoxins, fumonisins, deoxynivalenol, T-2 toxin, HT-2 toxin, patulin, zearalenone, and some ergot alkaloids are outlined. The wide variety of pathogenic mechanisms these compounds employ are shown capable of inducing a complex set of interactions. Of particular note are potential synergisms between mycotoxins with regard to carcinogenic attributable risk, indicating an important field for future study.

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Section: Aflatoxinsmentioning

confidence: 99%

Dietary mycotoxins, co-exposure, and carcinogenesis in humans: Short review

Ruyck

Boevre

Huybrechts

et al. 2015

Mutation Research/Reviews in Mutation Research

230

148

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“…Ozonolysis results in fragmentation of aflatoxin B1 and the products of this reaction include levulinic, succinic, malonic and glutaric acids (Van Drop et al, 1963). The presence of the lactone ring makes the compound labile to alkaline hydrolysis, and partial recyclization after acidification of the hydrolysis product has been reported (De Iongh et al, 1962). Although few systematic studies have been carried out on the stability of the aflatoxins, the general experience would seem to indicate that some degradation takes place under several conditions.…”

Section: Chemical Propertiesmentioning

confidence: 99%

Aflatoxins and Aflatoxicosis in Human and Animals

Dhanasekaran¹,

Shanmugapriya²,

Thajuddin³

et al. 2011

Aflatoxins - Biochemistry and Molecular Biology

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“…Although the detrimental health effects of aflatoxins and grain contamination have been known for over 50 years [1][2][3][4][5], a satisfactory solution has yet to be attained, from either a health or economic point of view. Since the publication of earlier reviews [6][7][8][9][10][11], encouraging advances have been achieved, but much remains to be done.…”

Section: Introduction To the Problemmentioning

confidence: 99%

Aflatoxin Resistance in Maize: What Have We Learned Lately?

Warburton

Williams

2014

Advances in Botany

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Aflatoxin contamination of maize grain is a huge economic and health problem, causing death and increased disease burden in much of the developing world and income loss in the developed world. Despite the gravity of the problem, deployable solutions are still being sought. In the past 15 years, much progress has been made in creating resistant maize inbred lines; mapping of genetic factors associated with resistance; and identifying possible resistance mechanisms. This review highlights this progress, most of which has occurred since the last time a review was published on this topic. Many of the needs highlighted in the last reviews have been addressed, and several solutions, taken together, can now greatly reduce the aflatoxin problem in maize grain. Continued research will soon lead to further solutions, which promise to further reduce and even eliminate the problem completely.

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Investigation of the factor in groundnut meal responsible for “turkey X disease”

Cited by 68 publications

References 2 publications

Dietary mycotoxins, co-exposure, and carcinogenesis in humans: Short review

Dietary mycotoxins, co-exposure, and carcinogenesis in humans: Short review

Aflatoxins and Aflatoxicosis in Human and Animals

Aflatoxin Resistance in Maize: What Have We Learned Lately?

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