Investigation on Cell Surface Markers of Dental Pulp Stem Cell Isolated from Impacted Third Molar Based on International  Society for Cellular Therapy Proposed Mesenchymal Stem Cell Markers

Sandra, Ferry; Sudiono, Janti; Feter, Yohanna; Afiana, Nadhia Sari; Chandra, Jessica Nathalia; Abdullah, Kharima; Shafira, Jasmine; Chouw, Angliana

doi:10.21705/mcbs.v3i1.34

Cited by 4 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…37 UC-MSCs are used more often than dental pulp stem cells (DPSCs), though dental pulp has been considered as an attractive source of MSCs due to its high cell content and relatively low invasive cell isolation procedure. 17,33,[38][39][40] DPSCs are similar to ASCs in their immunomodulatory properties. 33 There are 3 types of stem cell transplantation, i.e.…”

Section: Introductionmentioning

confidence: 99%

Safety and Efficacy of Mesenchymal Stem Cells in Burn Therapy: Systematic Review

Dini¹,

Nugraha²,

Revina³

et al. 2022

Mol Cell Biomed Sci

View full text Add to dashboard Cite

The experimental research on the use of mesenchymal stem cells (MSCs) for burn therapy has been published several times. However, current clinical procedure remains a challenging discussion. This systematic review assesses the safety and efficacy of administering mesenchymal stem cells (MSCs) to burns and determines the most effective source of MSCs for burn therapy. We reviewed several studies through PubMed, Google Scholar, Science Direct, and DOAJ online databases. PRISMA-P 2020 method was used based on inclusion and exclusion criteria that were re-selected through Joanna Briggs Institute (JBI) Critical Appraisal Tools. Results from 13 articles showed that MSCs are safe for burn therapy with minimal side effects/complications and have the potential to repair tissue and accelerate burn healing through several mechanisms. The treatment of MSCs in burns is influenced by donor characteristics and related to the severity and area of the burn. It can be concluded that the administration of MSCs is safe and effective in burn therapy. Keywords: burns, mesenchymal stem cells, therapeutic safety, therapeutic efficacy, wound healing

show abstract

Section: Introductionmentioning

confidence: 99%

Safety and Efficacy of Mesenchymal Stem Cells in Burn Therapy: Systematic Review

Dini¹,

Nugraha²,

Revina³

et al. 2022

Mol Cell Biomed Sci

View full text Add to dashboard Cite

show abstract

“…(41) A study demonstrates that SHED affect Based on the locations, dental stem cells are classified as dental pulp stem cell (DPSC), stem cells from human exfoliated deciduous teeth (SHED), stem cells from the apical papilla (SCAP), dental follicle stem cell (DFSC), periodontal ligament stem cell (PDLSC). (5,6) DPSCs, SHED, and DFSCs were reported to have potential in regenerating pulp-dentin complex in situ, both in animal models (Table 1) and human subjects (Table 2).…”

mentioning

confidence: 99%

Crucial Triad in Pulp-Dentin Complex Regeneration: Dental Stem Cells, Scaffolds, and Signaling Molecules

et al. 2023

View full text Add to dashboard Cite

BACKGROUND: Pulp damage can lead to dentinogenesis impairment, irreversible pulpitis, or pulp necrosis. Despite being the most used endodontic procedure to treat damaged pulp, root canal therapy only results in nonvital teeth which are prone to fractures and secondary infection. Pulp-dentin regeneration has a potential to regenerate structure similar to normal pulp-dentin complex, and can be achieved by combining dental stem cells, scaffold, and signaling molecules. This article reviews the role of various types of dental stem cells, scaffolds, signaling molecules, and their combinations in regenerating pulp-dentin complex.CONTENT: Dental pulp stem cell (DPSC), stem cell from human exfoliated deciduous teeth (SHED), and dental follicle stem cell (DFSC) were reported to regenerate pulp-dentin complex in situ. SHED might be more promising than DPSCs and DFSCs for regenerating pulp-dentin complex, since SHED have a higher proliferation potential and higher expression levels of signaling molecules. Scaffolds have characteristics resembling extracellular matrix, thus providing a suitable microenvironment for transplanted dental stem cells. To accelerate the regeneration process, exogenous signaling molecules are often delivered together with dental stem cells. Scaffolds and signaling molecules have different regenerative potential, including induction of cell proliferation and migration, formation of pulp- and/or dentin-like tissue, as well as angiogenesis and neurogenesis promotion.SUMMARY: Combinations of dental stem cells, scaffold, and signaling molecules are important to achieve the functional pulp-dentin complex formation. Current trends and future directions on regenerative endodontics should be explored. The right combination of dental stem cells, scaffold, and signaling molecules could be determined based on the patients’ characteristics. Incomplete pulp-dentin regeneration could be overcome by applying dental stem cells, scaffold, and/or signaling molecules in multiple visits.KEYWORDS: pulp-dentin regeneration, regenerative endodontics, dental stem cells, scaffold, signaling molecules

show abstract

The establishment of pulp polyp-derived mesenchymal stem cells with normal karyotype

Sandra,

Fibryanto,

Suwartini

et al. 2024

Journal of Dental Sciences

View full text Add to dashboard Cite

Investigation on Cell Surface Markers of Dental Pulp Stem Cell Isolated from Impacted Third Molar Based on International Society for Cellular Therapy Proposed Mesenchymal Stem Cell Markers

Cited by 4 publications

References 0 publications

Safety and Efficacy of Mesenchymal Stem Cells in Burn Therapy: Systematic Review

Safety and Efficacy of Mesenchymal Stem Cells in Burn Therapy: Systematic Review

Crucial Triad in Pulp-Dentin Complex Regeneration: Dental Stem Cells, Scaffolds, and Signaling Molecules

The establishment of pulp polyp-derived mesenchymal stem cells with normal karyotype

Contact Info

Product

Resources

About