Investigations on nickel ferrite embedded calcium phosphate nanoparticles for biomedical applications

Ruthradevi, T.; Akbar, Jefri; Kumar, G. Suresh; Thamizhavel, A.; Kumar, Gautam; Vatsa, R.K.; Dannangoda, G.C.; Martirosyan, Karen S.; Girija, E. K.

doi:10.1016/j.jallcom.2016.11.300

Cited by 38 publications

(21 citation statements)

References 37 publications

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“…In the past 20 years, NPs are the new research area that has attracted the attention of researchers because of their small size and unique physiochemical properties as chemical composition, solubility, shape, and aggregation behavior (Mahmood et al, 2010; Murdock et al, 2008; Schrand et al, 2010). NiFe 2 O 4 NPs are important molecules that have a great potential role for biomedical applications from their complex physicochemical properties (Ruthradevi et al, 2017). Nowadays, many advanced studies about nanotechnology and production of NPs are related to the negative and toxicological effects of NPs on human health (adverse effects on subcellular, cellular, tissue, organ, and protein levels) and environment (Dağlıoğlu et al, 2018; Elsaesser and Howard, 2012).…”

Section: Discussionmentioning

confidence: 99%

Genotoxic analysis of nickel–iron oxide in Drosophila

Nas

Çolak

2020

Toxicol Ind Health

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It is known that nickel–iron oxide nanocomposite (NiFe2O4NP) is used in many important areas such as modern industry, biomedical applications, magnetic resonance imaging, construction of sensors, targeted drug treatment, and photoelectric devices in our life. In this study, we have carried out a genotoxic evaluation of NiFe2O4NP (30 nm) in Drosophila melanogaster by using the wing somatic mutation and recombination assay. For this purpose, third instar larvae carrying the recessive genes ( flr3) and multiple wing hairs ( mwh) in their third chromosomes were used. The larvae were fed at concentrations ranging from 25 µg/mL to 200 µg/mL. The genotoxic effects of NiFe2O4NPs were evaluated according to mutant trichomes resulting from genetic changes (mitotic recombination, deletion, point mutation, nondisjunction) on development of the wing imaginal discs. Mutant clone evaluations were performed based on small single spots, large single spots, and twin spots classifications. The results showed that significant increases were observed in the frequency of all spots, indicating that the highest concentration of nanoparticles was able to induce genotoxic activity in the wing spot assay of D. melanogaster.

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Section: Discussionmentioning

confidence: 99%

Genotoxic analysis of nickel–iron oxide in Drosophila

Nas

Çolak

2020

Toxicol Ind Health

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“…Depending on their composition, the ferrites show soft- or hard-magnetic behavior. Despite some groups having found promising magnetic properties of soft-magnetic ferrites for certain medical applications only very few studies can be found in the literature [18,19,20,21]. Representative hard-magnetic ferrites with promising magnetic behavior for medical application are barium-, strontium- or cobalt-ferrite.…”

Section: The Core: Materials For Magnetic Nanoparticlesmentioning

confidence: 99%

Synthesis, Characterization, and Applications of Magnetic Nanoparticles Featuring Polyzwitterionic Coatings

et al. 2018

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Throughout the last decades, magnetic nanoparticles (MNP) have gained tremendous interest in different fields of applications like biomedicine (e.g., magnetic resonance imaging (MRI), drug delivery, hyperthermia), but also more technical applications (e.g., catalysis, waste water treatment) have been pursued. Different surfactants and polymers are extensively used for surface coating of MNP to passivate the surface and avoid or decrease agglomeration, decrease or modulate biomolecule absorption, and in most cases increase dispersion stability. For this purpose, electrostatic or steric repulsion can be exploited and, in that regard, surface charge is the most important (hybrid) particle property. Therefore, polyelectrolytes are of great interest for nanoparticle coating, as they are able to stabilize the particles in dispersion by electrostatic repulsion due to their high charge densities. In this review article, we focus on polyzwitterions as a subclass of polyelectrolytes and their use as coating materials for MNP. In the context of biomedical applications, polyzwitterions are widely used as they exhibit antifouling properties and thus can lead to minimized protein adsorption and also long circulation times.

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“…Tungsten carbide (WC) particles reinforced to zinc composite coatings improve their inherent mechanical bonding strengths [60]. Nickel and tungsten carbide particles were previously used to prepare coatings used for biomedical applications [54,[60][61][62]. It was confirmed from the above literature review that, the novel biocompatible Zn-Ni alloy and Zn-Ni-WC nanocomposites coatings are ideally best suited for a wide range of surface engineering applications.…”

Section: Introductionmentioning

confidence: 99%

“…In addition, electrodeposition based on low-cost coating techniques possessing precise control over thickness and thus reduced material waste that can offer complex profiled parts are not studied yet on zinc-nickel alloys and Zn-Ni-WC composites coating samples. The Ni metallic particles [61,62] and the WC nanoparticles (known for their biocompatibility) [54,60] are incorporated into the Zn coatings in a bath solution (10% diluted H 2 SO 4 + 90% diluted NaHCO 3 ), which are potentially stable and are not yet discussed in the open literature. In the present work, electrodeposited coatings (Zn-Ni alloy and Zn-Ni-WC: WC concentration of 1 g/L) were developed on the steel substrate and were examined with electrochemical tests (PC and EIS), followed by validation with non-electrochemical tests (XRD, SEM).…”

Section: Introductionmentioning

confidence: 99%

Electrodeposition Based Preparation of Zn–Ni Alloy and Zn–Ni–WC Nano-Composite Coatings for Corrosion-Resistant Applications

et al. 2021

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Zinc (Zn) is one of the five most widely consumed metals in the world. Indeed, more than 50% of all the zinc produced is used in zinc-galvanizing processes to protect steel from corrosion. Zn-based coatings have the potential for use as a corrosion-resistant barrier, but their wider use is restricted due to the poor mechanical properties of Zn that are needed to protect steel and other metals from rusting. The addition of other alloying elements such as Ni (Nickle) and WC (Tungsten Carbide) to Zn coating can improve its performance. This study investigates, the corrosion performance of Zn–Ni coating and Zn–Ni–WC composite nanocoatings fabricated on mild steel substrate in an environmentally friendly bath solution. The influence of WC nanoparticles on Zn–Ni deposition was also investigated. The surface morphologies, texture coefficients via XRD (X-ray diffraction), SEM (Scanning Electron Microscopy), and EDS (Energy-dispersive X-ray spectroscopy) were analyzed. The electrochemical test such as polarization curves (PC) and electrochemical impedance spectroscopy (EIS) resulted in a corrosion rate of 0.6948 Å/min for Zn–Ni–WC composite nanocoating, and 1.192 Å/min for Zn–Ni coating. The results showed that the Zn–Ni–WC composite nanocoating reduced the corrosion rate by 41.71% and showed an 8.56% increase in microhardness compared to the hardness of the Zn–Ni coating. These results are augmented to better wettable characteristics of zinc, which developed good interfacial metallurgical adhesion amongst the Ni and WC elements. The results of the novel Zn–Ni–WC nanocomposite coatings achieved a great improvement of mechanical property and corrosion protection to the steel substrate surface.

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Investigations on nickel ferrite embedded calcium phosphate nanoparticles for biomedical applications

Cited by 38 publications

References 37 publications

Genotoxic analysis of nickel–iron oxide in Drosophila

Genotoxic analysis of nickel–iron oxide in Drosophila

Synthesis, Characterization, and Applications of Magnetic Nanoparticles Featuring Polyzwitterionic Coatings

Electrodeposition Based Preparation of Zn–Ni Alloy and Zn–Ni–WC Nano-Composite Coatings for Corrosion-Resistant Applications

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