Investigations on sensitivity enhancement of SPR biosensor using tunable wavelength and graphene layers

Bhavsar, Kaushalkumar; Prabhu, Radhakrishna

doi:10.1088/1757-899x/499/1/012008

Cited by 8 publications

(4 citation statements)

References 17 publications

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“…This generated evanescent wave penetrates through the gold layer and propagates in the x-direction (fig 03). The magnitude of propagating wave vector in the x-direction can be expressed as [4]. Firstly we talk about the different components of our configuration sensor with their optical and other properties.…”

Section: Theory and Methodsmentioning

confidence: 99%

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Plasmonic biosensor for the study of blood diseases by analysis of hemoglobin concentration

2023

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Plasmonic materials and phenomena are widely studied and applied in multiple fields for an extended time. One among the foremost promising applications is within the engineering of biosensor devices, Diseases of the red blood cells are among the diseases of the blood. Anemia as an example is an abnormal reduction within the concentration of hemoglobin within the blood. When the amount of red blood cells decreases, so does the concentration of hemoglobin. The tissues and organs not receive sufficient oxygen to work normally. This numerical study will give a contribution or approach on the behavior of blood with surface plasmons resonance SPR by analyzing the performance of SPR with any changes in hemoglobin concentrations (refractive index) for the application of technique in the detection of blood diseases.

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Section: Theory and Methodsmentioning

confidence: 99%

“…The propagation vector of surface plasmon involves the refractive index of gold n2, and the hemoglobin n3, because the wave propagation at the metal-surrounding medium interface occurs partly in both the material. Therefore, the surface plasmon propagation vector, Ksp can be defined as [4].…”

Section: Spr and Blood Pathologiesmentioning

confidence: 99%

Plasmonic biosensor for the study of blood diseases by analysis of hemoglobin concentration

2023

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“…72,73 In the literature, the increase in the sensitivity depends on the number of graphene layers transferred over the metal thin film and the wavelength of the SPP and may be negligible at telecommunication wavelengths. 27,30,64 The decrease in FOM associated with increased sensitivity is not new in 2D-materials supported plasmonics, 74 and in most cases the effective result after 2D material transfer is similar to the deposition of a very thin layer film (<10 nm) with high refractive index over the external surface of SPR devices, which enhances the near electric field integral expressed by eq 3. 45 To further support our proposal, we link through Figure 8c,d the sensitivity of the devices with different interface configurations to the electromagnetic near-field distribution in the external environment, which controls the value of the normalized shift in the SPP wavevector δk norm , 45 reported in panel d. We observe the same trend in the histograms relative to the value of S RI and δk norm for the different experimental configurations, represented in panels b and d of Figure 8, respectively.…”

Section: S Ri and Fom Of The Au Thin-film Devices With Different Inte...mentioning

confidence: 99%

Water Diffusion Effects at Gold–Graphene Interfaces Supporting Surface Plasmon Polaritons

et al. 2022

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We present a detailed investigation on the effects of water diffusion at the different interfaces of gold−graphene plasmonic sensors on the propagation of the supported surface plasmon polaritons (SPPs). The substrate/metal interfacial chemical reactions are investigated by monitoring the full width at half-maximum of the SPR reflectivity curve. Although protection by singlelayer graphene (SLG) grown by chemical vapor deposition inhibits the chemical reactions happening at the metal−dielectric interfaces, SPR experimental results confirm that water diffusion paths through the borders of graphene domains are still present into the plasmonic sensors. Density functional theory calculations show that the doping level of SLG after the transfer on gold as well as interfacial charge transfer can be tuned in the presence of water molecules. On these bases, we propose a simplified effective medium approach for heterogeneous metal−carbon interfaces, where the interaction between the surface atomic layers of the gold thin film, water molecules, and the SLG induces the creation of an extended charge density difference region crossing the Au/H 2 O/SLG/H 2 O heterointerface. The latter is modeled as an ultrathin effective medium with a thickness and extraordinary optical susceptivity and conductivity that are different from those of the free-standing graphene. In this context, the extraordinary refractive index and thickness of the graphene−gold effective medium are measured in the near-infrared on the low-damping SPR platforms by applying the two-medium SPR method. The results are coherent with graphene n-doping in water environment, showing that the optically excited electrons along the extraordinary axis have a substantial bonding character and that the enhancement of the sensitivity of the gold−graphene plasmonic sensors is not related to a shift in the plasma frequency of the metal layer but to the changes in the extraordinary polarizability of graphene. The research highlights the importance of the SLG−substrate and SLG−environment interactions in graphene-protected plasmonics and optoelectronics.

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“…To overcome this issue, a theoretical approach is considered as an appropriate strategy. In doing so, numerous papers have proposed theoretical modeling of SPR biosensor based on the Kretschmann configuration (Widayanti & Abraha, 2016;Verma, Gupta, RajanJh, 2011;Maurya, Prajapati & Tripathi, 2018;Bhavsar & Prabhu, 2019;Dai et al, 2019;Zhao et al, 2018). However, most of the works (Brahmachari & Ray, 2013;Sadowski, Korhonen & Peltonen, 1995;Sarid & Challener, 2010) done in the formulation and analysis of SPR was employed 84 specialized software.…”

Section: Introductionmentioning

confidence: 99%

A Simple Simulation of Surface Plasmon Resonance in The Kretschmann Configuration Using Google Sheets

Quang

Anh

Hieu

2020

JPFI

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This article describes a simple numerical simulation of three-layer surface plasmon resonance (SPR) in the Kretschmann configuration. The calculation was performed in Google Sheets, a web-based spreadsheet environment that functions similarly to Microsoft Excel where it is easily accessible for students via the internet. Specifically, Fresnel’s equations were utilized to calculate the intensity of the reflected light for the p-polarized incident light on a three-layer system. The complex functions were utilized to plot the SPR curves. We examined the change of the resonance angle by the influence of the incident wavelength. The simulation was also performed for different thicknesses of the gold film layer. To demonstrate the sensitivity, we obtained the SPR curves with the variation of the refractive index in the sensitive medium. The SPR accuracy was analysed by comparing our obtained result with the published work. It is intended to incorporate into undergraduate instrumental analysis courses.

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Investigations on sensitivity enhancement of SPR biosensor using tunable wavelength and graphene layers

Cited by 8 publications

References 17 publications

Plasmonic biosensor for the study of blood diseases by analysis of hemoglobin concentration

Plasmonic biosensor for the study of blood diseases by analysis of hemoglobin concentration

Water Diffusion Effects at Gold–Graphene Interfaces Supporting Surface Plasmon Polaritons

A Simple Simulation of Surface Plasmon Resonance in The Kretschmann Configuration Using Google Sheets

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