Involvement of Catalase in Saccharomyces Cerevisiae Hormetic Response to Hydrogen Peroxide

Abstract

In this study, we investigated the relationship between catalase activity and H2O2-induced hormetic response in budding yeast S. cerevisiae. In general, our data suggest that: (i)hydrogen peroxide induces hormesis in a concentration- and time-dependent manner; and (ii) theeffect of hydrogen peroxide on yeast colony growth positively correlates with the activity ofcatalase that suggests the enzyme involvement in overall H2O2-induced stress response andhormetic response in yeast.

Choline-Based Ionic Liquids as Media for the Growth of Saccharomyces cerevisiae

“…The hormetic phenomena of microorganisms are often seen particularly in cases of short chained ILs [33]. Among them include a study conducted by Vasylkovska et al [26] whereby they investigated the hormesis effect of yeast against hydrogen peroxide. They concluded-with sufficient evidence that at low level of toxic concentration, it provided the organism with the potential to survive consequent lethal stress.…”

“…In unconventional surroundings, microorganisms tend to exhibit a dose-stimuli response (hormesis). The nature of the response depends highly on the agent that causes the stress, the intensity/duration of the stress, and also the physiological effect of the organism itself [26]. It is also interesting to note that in certain cases, hormesis activates certain defensive pathways that provides protection towards higher doses of the stress agent and sometimes towards other stressors as well.…”