Ionically and Covalently Crosslinked Hydrogel Particles Based on Chitosan and Poly(ethylene glycol)

Abstract

Self-assembled pH-sensitive reactive submicron-sized particles have been developed via intermolecular electrostatic interactions between chitosan and a carboxylated oligoperoxide having poly(ethylene glycol) fragments. The particles have the structure of an ionically crosslinked hydrogel and their size and surface charge depend on the conditions of their formation (i.e., pH and the functional group ratio). The presence of peroxide groups in the oligoperoxide has enabled to synthesize covalently crosslinked pH-sensitive particles.

Improving the Long-Term Performance of Poly(Vinyl Chloride)

“…Hydrogels are obtained both from natural organic raw materials [22][23][24] and from synthetic polymers. [25][26][27][28][29] Hydrogels based on poly-2-hydroxyethyl methacrylate (pHEMA) 30 and its copolymers 31,32 are distinguished from a wide range of synthetic highly hydrophilic polymers.…”

Preparation and Characteristics of Cationic Starches

“…Нині відомі методи одержання катіонних крохмалів, які використовують здебільшого у паперовій і текстильній промисловостях з невеликим ступенем заміщення амонійними фрагментами атомів гідрогену у макромолекулах крохмалю [6], як флокулянти колоїдних систем [7]. Комбінацією катіонних полісахаридів з аніонними поліелектролітами одержують поліелектролітні комплекси для формування гідрогелевих або дисперсних систем [8]. Широкого використання модифіко-вані крохмалі з аміногрупами у харчовій, косметичній і фармацевтичній промисловостях та для створення нових композиційних матеріалів не набули.…”

Improvement of Electrical Conductivity and Thermal Stability of Polyaniline-Maghnite Nanocomposites

“…The degree of deacetylation is a crucial component, because it impacts the physical characteristics of chitin. [3][4] Chitosan is a cationic polymer derived from N-deacetylated chitin which can be used as a dye adsorbent, 5 a matrix for drug delivery, [6][7] a therapy for mending wounds, 8 and an antibacterial agent against S. flava and B. cereus. 9 Chitosan units with a chemical formula 2-amino-2-deoxy-glucose and 2acetamino-dedoxy-D-glucose are connected through glycosidic bond (1 → 4).…”

“…9 Chitosan units with a chemical formula 2-amino-2-deoxy-glucose and 2acetamino-dedoxy-D-glucose are connected through glycosidic bond (1 → 4). 6 The previous works investigate the modification of chitosan from snail shells by the traditional method with a hot plate magnetic stirrer for antioxidant and hypercholesterolemia applications. This isolation approach changes the heat, temperature, and solvent during extraction.…”