Iris Transillumination Defects in the Pigment Dispersion Syndrome as Detected with Infrared Videography: A Comparision Between a Group of Blacks and a Group of Nonblacks

Clinical signs and characteristics of pigmentary glaucoma in Chinese

“…They are seen in 50%-86% of white patients, 4,6-9,12-14 but they are extremely rare among blacks. 4,6,[14][15][16][17] The literature contains …”

“…But in racial groups with dark irides, such as blacks and Chinese, TIDs should not be considered an equally important sign for the diagnosis of PG because they are not common in these racial groups. Roberts et al 4,[15][16][17] have proposed diagnostic criteria for black PG patients: moderate to heavy trabecular meshwork pigmentation and any degree of zonular or peripheral lenticular pigmentation. TIDs are not requisite for the diagnosis.…”

Clinical characteristics of pigment dispersion syndrome in Chinese patients

“…One of the most significant differences between these two phenotypes of PDS is that black patients do not have midperipheral radial ITDs. [8][9][10][11][12][13] Although common in white PDS patients, anterior iris stromal pigment granule dusting is rare in their black counterparts, probably because of dark irides in these patients. The results of our study have shown that the clinical features of PDS in Chinese are more like that of blacks.…”

“…8,11,13 There are a greater content of pigment granules in melanocytes and iris stroma in dark irides than in light ones. As such, they can block an IPE transillumination defect.…”

“…Some clinical signs that are consistently present in white patients such as ITDs and anterior iris stromal pigment dusting are, however, not as common in blacks. [8][9][10][11][12][13] To characterize the clinical features of PDS in Chinese, we carried out a prospective observational investigation on a consecutive series of 18 Chinese patients identified as having PDS according to the identical diagnostic criteria.…”