Iron(iii) selective molecular and supramolecular fluorescent probes

Abstract

Iron is one of the most important elements in metabolic processes, being indispensable for all living systems and therefore it is extensively distributed in environmental and biological materials. However, both its deficiency and excess from the normal permissible limit can induce serious disorders. Therefore, several analytical techniques have been adopted for the detection of iron. Among the various techniques used for its detection, the method based on fluorescent sensors has received considerable interest in recent years because of its ability to provide online monitoring of very low concentrations without any pre-treatment of the sample together with the advantages of spatial and temporal resolution. In this article, efforts have been made to review the various molecular and supramolecular fluorescent sensors that have been developed for the selective detection of iron(III).

A new Rhodamine B derivative RBMAB as a highly selective and sensitive chemosensor for Fe3+ with low detection limit

“…6 Many techniques for detecting Fe 3+ have been reported, including atomic absorption spectrometry, 7,8 voltammetry, 9 fluorometric and colorimetric method. [10][11][12][13] Many are complicated and not suitable for quick and online monitoring. Among these methods, fluorometric assay with specific fluorescence chemosensor is currently attracting much attention as a method to reveal the molecular functions of the ions in living systems.…”

A Rhodamine-based Dual Chemosensor for the Simultaneous Detection of Fe3+ and Cu2+

“…14,22,23 Compared with traditional one-to-one normal sensors and their corresponding analytical methods, a dual sensor can recognize multiple targets metal ions simultaneously by a chemosensor using a single detection methods, or an array of detection methods, which makes it more efficient, more versatile, less expensive, and widens its range of applicability with operational simplicity. 1,14,[23][24][25] The Rhodamine-based sensors for detecting metal ions were collected, and are listed in Table 1. As shown in Table 1, the Rhodamine-based dual sensor with high sensitivity and selectivity toward Fe 3+ and Cu 2+ simultaneously has not yet been studied in-depth.…”

A novel fluorescent “turn-on” chemosensor for nanomolar detection of Fe(III) from aqueous solution and its application in living cells imaging

“…It is worth noting that many reported fluorescent "turn-on" chemosensors for the Fe 3 þ ion utilize the rhodamine moiety due to its advantageous photophysical properties (Sahoo et al, 2012). However, some rhodamine dyes are harmful if swallowed by humans or animals, and cause irritation of the skin, eyes and respiratory tract (Jain et al, 2007;Rochat et al, 1978).…”

“…The development of highly selective and sensitive chemosensors for bioactive metal ions has gained enormous importance (Au-Yeung et al, 2013;Callan et al, 2005;Chen et al, 2012;Dutta and Das, 2012;Formica et al, 2012;Kim et al, 2012;Sahoo et al, 2012), as metal ions are well known to be involved in a variety of fundamental biological processes, which are essential for maintaining the life of organisms and remain sustainable under environmental conditions. As an important physiologically relevant metal ion, Fe 3 þ exhibits an obligatory role in many biochemical processes at the cellular level.…”