We report measurements of the electron g-factor in InSb quantum wells using the coincidence technique, polarization transition, and temperature-dependent resistivity. All three methods show that there is a giant enhancement of the spin slitting which is proportional to the spin polarization. Electron Zeeman energies as high as 51 meV are measured leading to the conclusion that the additional contribution to the spin splitting is of order 30 meV, more than ten times larger than expected from conventional theories.