Isoconversional thermal and pyrolytic GC–MS analysis of street samples of hashish

Iqbal, Mohammad S.; Khan, Muhammad Umar Aslam; Akbar, Jamshed; Shad, Muhammad Aslam; Masih, Rashid; Chaudhary, Muhammad Taimoor

doi:10.1016/j.jaap.2016.09.026

Cited by 8 publications

(5 citation statements)

References 13 publications

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“…Terpenoid degradation in the context of cannabis has not been extensively studied; 3 , 4 however, it has attracted attention in the context of atmospheric chemistry. 5 , 6 For instance, the reactions of terpenoids with O 3 and NO x are well-known, but they are not directly applicable to e-cigarettes or inhalable cannabis products.…”

Section: Introductionmentioning

confidence: 99%

“…Terpenoid degradation in the context of cannabis has not been extensively studied; , however, it has attracted attention in the context of atmospheric chemistry. , For instance, the reactions of terpenoids with O 3 and NO x are well-known, but they are not directly applicable to e-cigarettes or inhalable cannabis products. However, these and other studies of pyrolysis and combustion of terpenoids should serve as a starting point toward understanding the reaction pathways in consumer vaporization devices.…”

Section: Introductionmentioning

confidence: 99%

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Toxicant Formation in Dabbing: The Terpene Story

2017

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Inhalable, noncombustible cannabis products are playing a central role in the expansion of the medical and recreational use of cannabis. In particular, the practice of “dabbing” with butane hash oil has emerged with great popularity in states that have legalized cannabis. Despite their growing popularity, the degradation product profiles of these new products have not been extensively investigated. The study herein focuses on the chemistry of myrcene and other common terpenes found in cannabis extracts. Methacrolein, benzene, and several other products of concern to human health were formed under the conditions that simulated real-world dabbing. The terpene degradation products observed are consistent with those reported in the atmospheric chemistry literature.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Toxicant Formation in Dabbing: The Terpene Story

2017

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“…After 72 h of contact time with composite hydrogels and curcumin-BSG-4 composite hydrogels, nearly 79.56 to 87.58 percent of U87 cells were determined to be nonviable, respectively, as exhibited in Figure 8 a. Curcumin combined with PVA/BC- f -GO was discovered to have improved anticancer properties. The BSG-4 composite hydrogel also had the highest cell nonviability among the composite hydrogels, which could be owing to the increased GO content [ 20 , 39 ]. The curcumin-loaded-BSG-4 had the strongest antitumor effect.…”

Section: Resultsmentioning

confidence: 99%

pH-Responsive PVA/BC-f-GO Dressing Materials for Burn and Chronic Wound Healing with Curcumin Release Kinetics

et al. 2022

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Polymeric materials have been essential biomaterials to develop hydrogels as wound dressings for sustained drug delivery and chronic wound healing. The microenvironment for wound healing is created by biocompatibility, bioactivity, and physicochemical behavior. Moreover, a bacterial infection often causes the healing process. The bacterial cellulose (BC) was functionalized using graphene oxide (GO) by hydrothermal method to have bacterial cellulose-functionalized-Graphene oxide (BC-f-GO). A simple blending method was used to crosslink BC-f-GO with polyvinyl alcohol (PVA) by tetraethyl orthosilicate (TEOS) as a crosslinker. The structural, morphological, wetting, and mechanical tests were conducted using Fourier-transform infrared spectroscopy (FTIR), Scanning electron microscope (SEM), water contact angle, and a Universal testing machine (UTM). The release of Silver-sulphadiazine and drug release kinetics were studied at various pH levels and using different mathematical models (zero-order, first-order, Higuchi, Hixson, Korsmeyer–Peppas, and Baker–Lonsdale). The antibacterial properties were conducted against Gram-positive and Gram-negative severe infection-causing pathogens. These composite hydrogels presented potential anticancer activities against the U87 cell line by an increased GO amount. The result findings show that these composite hydrogels have physical-mechanical and inherent antimicrobial properties and controlled drug release, making them an ideal approach for skin wound healing. As a result, these hydrogels were discovered to be an ideal biomaterial for skin wound healing.

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“…The surface morphology of the bioactive polymeric scaffolds was examined using SEM as shown in Figure 6 . The various magnifications exhibit rough and porous topography of polymeric bioactive scaffolds (evident from the XRD results), which remarkably encourage cell adhesion and proliferation on the scaffold [ 32 , 33 ]. At higher magnification, however, the SEM images show a specific porous morphology which also supports cell infiltration, adhesion and extracellular matrix secretion.…”

Section: Resultsmentioning

confidence: 99%

Development of Polymeric Nanocomposite (Xyloglucan-co-Methacrylic Acid/Hydroxyapatite/SiO2) Scaffold for Bone Tissue Engineering Applications—In-Vitro Antibacterial, Cytotoxicity and Cell Culture Evaluation

et al. 2020

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Advancement and innovation in bone regeneration, specifically polymeric composite scaffolds, are of high significance for the treatment of bone defects. Xyloglucan (XG) is a polysaccharide biopolymer having a wide variety of regenerative tissue therapeutic applications due to its biocompatibility, in-vitro degradation and cytocompatibility. Current research is focused on the fabrication of polymeric bioactive scaffolds by freeze drying method for nanocomposite materials. The nanocomposite materials have been synthesized from free radical polymerization using n-SiO2 and n-HAp XG and Methacrylic acid (MAAc). Functional group analysis, crystallinity and surface morphology were investigated by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction analysis (XRD) and scanning electron microscopy (SEM) techniques, respectively. These bioactive polymeric scaffolds presented interconnected and well-organized porous morphology, controlled precisely by substantial ratios of n-SiO2. The swelling analysis was also performed in different media at varying temperatures (27, 37 and 47 °C) and the mechanical behavior of the dried scaffolds is also investigated. Antibacterial activities of these scaffolds were conducted against pathogenic gram-positive and gram-negative bacteria. Besides, the biological behavior of these scaffolds was evaluated by the Neutral Red dye assay against the MC3T3-E1 cell line. The scaffolds showed interesting properties for bone tissue engineering, including porosity with substantial mechanical strength, biodegradability, biocompatibility and cytocompatibility behavior. The reported polymeric bioactive scaffolds can be aspirant biomaterials for bone tissue engineering to regenerate defecated bone.

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Isoconversional thermal and pyrolytic GC–MS analysis of street samples of hashish

Cited by 8 publications

References 13 publications

Toxicant Formation in Dabbing: The Terpene Story

Toxicant Formation in Dabbing: The Terpene Story

pH-Responsive PVA/BC-f-GO Dressing Materials for Burn and Chronic Wound Healing with Curcumin Release Kinetics

Development of Polymeric Nanocomposite (Xyloglucan-co-Methacrylic Acid/Hydroxyapatite/SiO2) Scaffold for Bone Tissue Engineering Applications—In-Vitro Antibacterial, Cytotoxicity and Cell Culture Evaluation

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