Isoflavonoids and chalcones from Anthyllis hermanniae

Efflux Pumps Are Involved in the Defense of Gram-Negative Bacteria against the Natural Products Isobavachalcone and Diospyrone

“…Isobavachalcone has been isolated from several medicinal plants (20,21,24). Isobavachalcone was reported to have very interesting activities against Candida albicans and Cryptococcus neoformans (9), and some preliminary results have indicated that this compound has activity against susceptible microorganisms (20).…”

Inhibitory Effects of Bakuchiol, Bavachin, and Isobavachalcone Isolated fromPiper longumon Melanin Production in B16 Mouse Melanoma Cells

“…The compounds were identified by comparison of their spectral data (UV, ½ D , MS, and NMR) with data previously reported. [11][12][13][14][15][16] Next, compounds 1-3 were examined with regard to their ability to suppress melanin biosynthesis in B16 cells. The addition of the isolated compounds to the cells prior to stimulation with 100 nM -MSH markedly decreased the production of melanin, in a dose-dependent manner (Fig.…”

Flavanoids and Pterocarpans from the Bark of Erythrina fusca

“…The EtOAc extract of E. fusca bark was separated by extensive column chromatography to give three new isomeric flavanones, named fuscaflavanones A 1 (1), A 2 (2) and B (3), along with six known flavanones, lupinifolin (4), 9) lonchocarpol A (5), 10,11) a mixture of lonchocarpols C 1 and C 2 (6a, b), 11,12) a mixture of lonchocarpols D 1 and D 2 (7a, b), 12) five pterocarpans, sandwicensin (8), 6,13) phaseollidin (9), 14) erythrabissin I (10), 14) and a mixture of dolichins A and B (11a, b), 15) one chalcone, isobavachalcone (12), 16) and one isoflavone, wighteone (13) 17,18) ( Fig. 1).…”