Isolated Polycystic Liver Disease: An Unusual Cause of Recurrent Variceal Bleed

Abstract

Isolated polycystic liver disease is a rare disorder. Majority of the patients with isolated polycystic liver disease are asymptomatic with incidental detection of liver cysts on imaging studies done for other purposes. Minority of patients develop symptoms which are mostly secondary to enlarging cysts size and hepatomegaly. Rarely, these patients develop portal hypertension and can present with its clinical manifestations and consequences in the form acute variceal bleeding or recurrent ascites. We present a rare case of 67-year-old female patient with significant history of polycystic liver disease who presented to the hospital with recurrent hematemesis and melena. She underwent esophagogastroduodenoscopy which showed multiple large esophageal varices requiring banding.

Polycystic Liver Disease: A Case Report

“…Other complications may be related with infection of liver cyst and rupture of liver cyst which may cause hemorrhage and severe acute pain. 7 There are two PLD-specific questionnaires to evaluate PLD-related symptoms and gauged the PLD disease burden, which are POLCA (PLD complainspecific assessment) and PLD-Q (PLD questionnaire). 1 Abdominal USG is the first line of imaging modality to detect PLD as it readily available in most hospital settings, inexpensive, and no radiation.…”

Doença Hepática Policística Adulta: Relato De Caso

“…De toda forma, nos casos de infecção, é imprescindível o reconhecimento e tratamento precoce para reduzir o risco de complicações fatais, através da administração de antibióticos e, em alguns casos, drenagem destes cistos. 9 Grande parte dos pacientes não precisarão de tratamento, visto que a maioria é assintomática. 3 No entanto, na porcentagem que apresenta sintomas, a abordagem terapêutica será dividida em manejo sintomático e em intervenção cirúrgica.…”

Management of portal hypertension and ascites in polycystic liver disease

“…12 Variceal haemorrhage has been described in only six cases. [32][33][34][35][36][37] For management of varices, we refer to the relevant guidelines. 38,39…”

“…The prevalence of varices was also 2% in patients listed for liver transplantation . Variceal haemorrhage has been described in only six cases . For management of varices, we refer to the relevant guidelines …”