Isolation and Structure Elucidation of Armillaricin¹

Abstract

From the petroleum ether extracts of the artificially cultured mycelium of ARMILLARIA MELLEA, a novel sesquiterpenoid aromatic ester named armillaricin has been isolated by silica gel column chromatography. Its structure was deduced from spectral data and confirmed by single-crystal X-ray analysis.

Effect of submerged culture conditions on exopolysaccharides production by Armillaria luteo-virens Sacc QH and kinetic modeling

“…Furthermore, polysaccharides extracted from the mycelia of A. mellea karst significantly inhibit mutation and tumor cells [9]. A. mellea has been used in the treatment of geriatric patients with palsy, dizziness, headache, neurasthenia, and insomnia, numbness in limbs, and so on [10]. A. luteo-virens Sacc is reported to display some distinctive characteristics as compared to fungus A. mellea [11].…”

Improvement of exo-polysaccharides production and modeling kinetics by Armillaria luteo-virens Sacc. in submerged cultivation

“…could significantly inhibit mutation and tumor cell (Chen, Bi, & Chen, 2004). A. mellea (Tricholomataceae) has been reportedly used in the treatment of geriatric patients with palsy, dizziness, headache, neurasthenia, insomnia, numbness in limbs, and infantile convulsion, and other effects (Fraser & Lindberg, 1967;Yang et al, 1989). There were several reports that A. luteo-virens Sacc.…”

New Biologically Active Metabolites from Chinese Higher Fungi

“…The culture mycelia of this ascomycete yielded a new diterpenoid, resenonolactone (58) [45]. Another monocyclic diterpenoid metabolite, moreloriol (59), was obtained from the mycelia of Morchella conica Pers. (Mochellaceae) [46].…”