Isolation of herpes virus from erythema multiforme.

Macdonald, A.; Feiwel, M

doi:10.1136/bmj.2.5813.570

Cited by 33 publications

(9 citation statements)

References 3 publications

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“…Herpes sim plex infection is associated with it [7][8][9] as is mycoplasma infection [10] as well as other infectious processes [11][12][13][14][15]. Drugs [16][17][18][19][20][21][22] 384 Nethercott/Choi are commonly associated.…”

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confidence: 99%

Erythema multiforme (Stevens-Johnson Syndrome) – Chart Review of 123 Hospitalized Patients

Nethercott

Choi

1985

Dermatology

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The charts of 123 patients hospitalized with erythema multiforme were reviewed. Antecedent infections and the administration of drugs were associated with 15 and 32% of the cases, respectively. Pyrexia arthralgia, photosensitivity, abnormal liver function tests and abnormal urine sediment were common findings. The length of stay in hospital was 12.6 ± 0.7 days (mean ± SE), time to initial improvement after onset was 10.3 ± 0.6 days and time to complete resolution was 23.0 ± 2.4 days. The presence of bullous skin lesions and greater overall severity were associated with longer hospitalization. Antecedent respiratory tract symptoms were related to shorter hospitalization. Steroid therapy was not associated with a shorter time for initial improvement to occur, while the average length of stay in hospital was 4.2 days longer than that for the patients not treated with corticosteroid.

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confidence: 99%

Erythema multiforme (Stevens-Johnson Syndrome) – Chart Review of 123 Hospitalized Patients

Nethercott

Choi

1985

Dermatology

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“…Dies wird in der Literatur haufig als auslosender Faktor fiir das Stevens-Johnson-Syndrom bei Kindern beschrieben [6]. Zusatzlich ausschlaggebend war die Medikamentenanamnese, in der sich die Einnahme von oralen Antibiotika fand.…”

Section: Resultateunclassified

“…Die Krankheitsdauer betragt etwa 1-6 Wochen. 50-60% der Fdlle sind medikamentos induziert (hauptsachlich durch Sulfonamide) [2,3]; es tritt aber auch nach Gabe topischer Augenmedikamente (Scopolamin, Sulfonamide, Tropicamid) [4,5], sowie postinfektios (HerpesSimplex-Virus, Mykoplasmen Pneumonie, Maseru) [6,7] auf Eine genetische Predisposition fir die Entwicklung eines Stevens-Johnson-Syndrom mit okularer Beteiligung wird diskutiert. Die humanen Leukozyten-Antigene HLA-Bw44 and HLA-B12 scheinen damit assoziiert zu sein [8].…”

Section: Hintergrundunclassified

Stevens-Johnson-Syndrom — eine interdisziplinäre Herausforderung

Oser

Pinter

Hausmann

2005

Spektrum Augenheilkd

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“…All available evidence suggests that a diverse group of agents, infectious, chemical, and neoplastic, can lead, in certain individuals, to the production and deposition of immune complexes in the dermal blood vessels. Although infectious agents such as herpes simplex virus [31,45] and Mycoplasma pneumoniae [14,30] have been cultured from lesions of erythema multiforme, these findings have been only seen in isolated cases. The present state of knowledge suggests that a more generalized hypersensitivity state mediates this disorder.…”

Section: Resultsmentioning

confidence: 99%