Isseminated Superficial Actinic Porokeratosis in Patient Suffering From Plaque Psoriasis: A Case Report

ZNAMENSKAYA, L F; Знаменская, Л Ф; Чикин, В. В.; Kappusheva, I A; Kondrasheva, V. V.; Кондрашова, В. В.

doi:10.25208/0042-4609-2015-91-5-91-96

Vestnik dermatologii i venerologii

2015

DOI: 10.25208/0042-4609-2015-91-5-91-96

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Isseminated Superficial Actinic Porokeratosis in Patient Suffering From Plaque Psoriasis: A Case Report

L F ZNAMENSKAYA

Л Ф Знаменская²,

В. В. Чикин

et al.

Abstract: Monitoring of disseminated superficial actinic porokeratosis (DSAP) in patient suffering from plaque psoriasis treated by PUVA therapy was presented. DSAP is a rare skin disease developing in the result of keratosis disorder caused by solar radiation and appearing as clearly localized ringed or line plates. As patients with DSAP are sensitive to solar radiation, phototherapy is contraindicated for them. In this regard, subcutaneous injections of Methotrexate 10 mg once a week were prescribed to a patient suffe… Show more

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Cited by 2 publications

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Porokeratosis and its clinical variants

Потекаев¹,

Akimov²,

Fomina³

et al. 2019

Klin. dermatol. venerol.

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Представлены собственные наблюдения нескольких клинических вариантов порокератоза, описаны генетические с аутосомно-доминантным типом наследования и средовые факторы, включающие интенсивность инсоляции, сопутствующие заболевания, лекарственно индуцированную иммуносупрессию, способствующие его возникновению. Согласно современной классификации, выделяют локализованные и диссеминированные формы. К локализованным относят порокератоз Мибелли, линейный порокератоз, ладонно-подошвенный точечный, генитальный, перианальный порокератоз; к диссеминированным-поверхностный актинический, поверхностный диссеминированный, диссеминированный ладонно-подошвенный, систематизированный линейный порокератоз. Многообразие форм порокератоза при идентичности гистологических признаков позволяет считать их клиническими вариантами одного заболевания. Методы лечения включают как наружную терапию-цитостатические препараты, аналоги витамина D 3 , иммуномодуляторы, ингибиторы кальциневрина, ретиноиды, так и системную-ретиноиды, а также хирургическое иссечение очагов, криотерапию, электродиссекцию и кюретаж образований, дермабразию очагов и фотодинамическую терапию. Кроме того, пациенты должны быть информированы об использовании солнцезащитных средств и эмолиентов. Выбор метода лечения определяется формой заболевания, локализацией, прогнозом, а также косметическими показаниями. Важны своевременная диагностика и наблюдение за пациентами, страдающими порокератозом (особенно линейной формой), и лицами с иммуносупрессией, поскольку риск возникновения плоскоклеточного рака кожи в очагах у таких пациентов повышен.

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Porokeratosis and its clinical variants

Потекаев¹,

Akimov²,

Fomina³

et al. 2019

Klin. dermatol. venerol.

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Can the lesions induced with actinic keratosis become an enigma for dermatologists? Results of an open perspective study

Bujnauskajte

Buinauskaitė²,

Rubins

et al. 2017

Vestnik dermatologii i venerologii

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Different face skin diseases (basal cell carcinoma, actinic keratosis, rosacea, solar elastosis, etc.) could clinically manifest itself as erythematic patches, pimples or plagues. It is very hard to make the clinical exclusion in some cases of these diseases since their characters can partially overlap or certain lesion can mimic another one especially in the cases of skin areas affected with sun. Therefore, the histopathological analysis remains the “golden standard” of the dermatological diagnosis at skin diseases. Our study has shown that certified dermatologists detect actinic keratosis (AK) of face/head skin of I/II levels very well. Verdicts of dermatologists and pathomorfologists are congruent on account of diagnosis in 90,7% cases. Diseases clinically excluded as AK revealed as malignant neoplasms (basal cell carcinoma) in less than 1% of case lesions.

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Isseminated Superficial Actinic Porokeratosis in Patient Suffering From Plaque Psoriasis: A Case Report

Cited by 2 publications

References 30 publications

Porokeratosis and its clinical variants

Porokeratosis and its clinical variants

Can the lesions induced with actinic keratosis become an enigma for dermatologists? Results of an open perspective study

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