The program disturbance characteristics of three-dimensional (3D) vertical NAND flash cell array architecture pose a critical reliability challenge due to the lower unselected word line (WL) pass bias (Vpass) window. In other words, the key contradiction of program disturbance is that the operational Vpass during the program’s performance cannot be too high or too low. For instance, the 3D NAND program’s operation string needs a lower Vpass bias to suppress unselected WL Vpass bias-induced Fowler–Nordheim tunneling (FN tunneling), but for the inhibited string, the unselected WL needs a higher Vpass bias to suppress selected WL program bias (Vpgm)-induced FN tunneling. In this paper, a systematical insight into the relationship between the channel potential and channel electron density is given. Based on this intensive investigation, we studied a novel channel preparation scheme using “Gate-induced drain leakage (GIDL) pre-charge”. Our methodology does not require the introduction of any new structures in 3D NAND, or changes in the operational Vpass bias. Instead, the potential on the unselected channel is enhanced by exploiting the holes generated by the GIDL operation effectively, leading to significantly suppressed program disturbance and a larger pass disturb window. To validate the effectiveness of the “GIDL pre-charge” method, TCAD simulation and real silicon data are used.