“…Cystica profunda has a high incidence of concurrence with other diseases that tend to irritate the bowel, such as ulcerative colitis, Crohn's disease, adenomatous polyps, Peutz-Jeghers syndrome, and spastic colitis. 7,9,10 Enteritis cystica profunda has been simulated in rats by suturing the small intestine to the abdominal wall and then exposing the mucosa externally. 11 Other hypothetical explanations for ECP are epithelial downgrowth through ulcerated mucosa, herniation through a weakened muscularis mucosa, re-epithelization of a submucosal abscess, and hemorrhage.…”