Kinetische Analyse der Isoenzymverteilung von Lactatdehydrogenase im Plasma w�hrend der Geburt

Unbehaun, V.; Waidmann, B.; Jung, Gerhard

doi:10.1007/bf00673655

Cited by 2 publications

(1 citation statement)

References 33 publications

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“…Skeletal muscle could also be the tissue, from which L D H partly originates during labor, as suggested by Unbehaun et a/. (39). Another possible source of the elevated L D H 5 during labor could be the amniotic fluid cells, since these tend to show increasing L D H 5 as pregnancy progresses (30), and a n increase of LDH 5 in amniotic fluid with increasing gestational age has been confirmed (29).…”

Section: Arta Obsret Gynecolmentioning

confidence: 82%

Serum Lactic Acid Dehydrogenase and Isoenzymes During Pregnancy and Labor

Makkonen¹,

Penttilä²,

Castrén³

1980

Acta Obstet Gynecol Scand

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Total serum lactic acid dehydrogenase activity (LDH) and the levels of LDH isoenzymes were investigated in 14 women during early pregnancy (8--16th week), in 28 women during late pregnancy (29--37th week), in 73 at term (38--42nd week) and in 27 during labor (38--42nd week). LDH activity was found to be elevated in severe pre-eclampsia and in chronic hypertensive women during pregnancy as well as during normal and dysfunctional labor. No change was established in total serum LDH during normal pregnancy. LDH 1 was increased during late pregnancy and at term. In severe pre-eclampsia and during normal labor it was decreased. LDH 2 was also decreased in severe pre-eclampsia and during dysfunctional labor. LDH 3 was decreased during late pregnancy but increased in severe pre-eclampsia. No change was observed in LDH 4 during pregnancy, or in labor. LDH 5 was increased in normal and dysfunctional labor.

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Section: Arta Obsret Gynecolmentioning

confidence: 82%

Serum Lactic Acid Dehydrogenase and Isoenzymes During Pregnancy and Labor

Makkonen¹,

Penttilä²,

Castrén³

1980

Acta Obstet Gynecol Scand

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Über das Verhalten klinisch‐chemischer Serumbestandteile bei Traberstuten während der Hochträchtigkeit und in der frühen Laktation

Jaeschke¹,

Muller

1975

Reprod Domestic Animals

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Inhalt: Bei 15 Traberstuten im Alter von 10 bis 25 Jahren wurde das Verhalten der Laktatdehydrogenase (LDH), der alkalischen Phosphatase (APhH) and des freien Hydroxyprolins (FHP) während der Hochträchtigkeit und in der frühen Laktation bis zu 60 Tagen post partum untersucht. Diese Metaboliten liefern klinisch‐chemisch relevante Daten über die Unterusinvolution bei der Stute. Zusammenfassend wurden folgende Befunde im Serum erhoben: 1. Die LDH, die als Indikator für die Atrophie des Myometriums in diesem Stadium angesehen werden kann, stieg gegen Ende der Trächtigkeit leicht and nach der Geburt stark an. Der Serumspiegel war bis zu 27 Tagen post partum deutlich erhöht. 2. Die alkalische Phosphatase fiel gegen Ende der Trächtigkeit im Serum signifikant ab, stieg kurz nach der Geburt rasch über die Norm an und war noch nach 2 Monaten beträchtlich erhöht. Als Herkunftsorgan wird in dieser Phase hauptsächlich das Endometrium vermutet. 3. Das Hydroxyprolin als Maβ für den uterinen Kollagenabbau verhielt sich während der Trächtigkeit unterschiedlich, stieg aber nach der Geburt einheitlich urn das Doppelte an und erreichte erst nach 30 Tagen wieder die Norm. Die miteinander korrelierenden Parameter werden im Zusammenhang mit puerperalen Fruchtbarkeitsstörungen diskutiert. Contents: The behaviour of chemical components of serum of trotting mares during late pregnancy and in early lactation. 2. Communication: biochemical indicators for the involution of the uterus. The level of lactic dehydrogenase (LDH), alkaline phosphatase (APh) and free hydroxyproline (FHP) was determind in the serum of 15 trotter mares ranging in age between 10 and 15 years. This was undertaken during late pregnancy and early lactation till 60 days post‐partum. These metabolites are important indicators for the involution of the uterus in the mare. 1. The LDH, which could be taken as an indicator for the athrophy of the myometrium, was observed to increase slightly toward the end of pregnancy and greatly after parturition. However, a clear increase was detected in the serum level till 27 days post‐partum. 2. The level of alkaline phosphatase decreased significantly towards the termination of pregnancy, to increase abruptly shortly after parturition about the normal values and remained high 2 month. It is prosumed that these changes originated at this phase in the endometrium. 3. Hydroxyproline, an indicator of collagen metabolism, showed a variable picture during pregnancy. However it doubled after parturition and returned to the normal level after 30 days. The relationship between these parameters and its influence on fertility was discussed.

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Kinetische Analyse der Isoenzymverteilung von Lactatdehydrogenase im Plasma w�hrend der Geburt

Cited by 2 publications

References 33 publications

Serum Lactic Acid Dehydrogenase and Isoenzymes During Pregnancy and Labor

Serum Lactic Acid Dehydrogenase and Isoenzymes During Pregnancy and Labor

Über das Verhalten klinisch‐chemischer Serumbestandteile bei Traberstuten während der Hochträchtigkeit und in der frühen Laktation

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