Kognitionsverb i sverigesvenska och finlandssvenska handledningssamtal

Nelson, Marie; Henricson, Sofie

doi:10.23997/pk.69809

Cited by 4 publications

(2 citation statements)

References 5 publications

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“…Specific example (HHr): G12(3cG) mutation 36 (k/k' >200) that leads to upshifting of the pK a at the N1 41 , and gives rise to a (normal) secondary γ effect.…”

Section: Perturbations Affecting γ Catalysismentioning

confidence: 99%

An Ontology for Facilitating Discussion of Catalytic Strategies of RNA-Cleaving Enzymes

et al. 2019

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A predictive understanding of the mechanisms of RNA cleavage is important for the design of emerging technology built from biological and synthetic molecules that have promise for new biochemical and medicinal applications. Over the past 15 years, RNA cleavage reactions involving 2'-O-transphosphorylation have been discussed using a simplified framework introduced by Breaker that consists of four fundamental catalytic strategies (designated α, β, γ, and δ) that contribute to rate enhancement. As more detailed mechanistic data emerge, there is need for the framework to evolve and keep pace. We develop an ontology for discussion of strategies of enzymes that catalyze RNA cleavage via 2'-O-transphosphorylation that stratifies Breaker's framework into primary (1°), secondary (2°) and tertiary (3°) contributions to enable more precise interpretation of mechanism in the context of structure and bonding. Further, we point out instances where atomic-level changes give rise to changes in more than one catalytic contribution, a phenomenon we refer to as 'functional blurring'. We hope that this ontology will help clarify our conversations and pave the path forward toward a consensus view of these fundamental and fascinating mechanisms. The insight gained will deepen our understanding of RNA cleavage reactions catalyzed by natural protein and RNA enzymes, as well as aid in the design of new engineered DNA and synthetic enzymes.

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“…Specific example (HHr): G12(3cG) mutation 36 (k/k' >200) that leads to upshifting of the pK a at the N1 41 , and gives rise to a (normal) secondary γ effect.…”

Section: Perturbations Affecting γ Catalysismentioning

confidence: 99%

An Ontology for Facilitating Discussion of Catalytic Strategies of RNA-Cleaving Enzymes

et al. 2019

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“…In addition to the mitigation in line 1, it highlights how the counsellor more or less steps into domains of which the student has first-hand knowledge to provide an account on behalf of the student and indicate that the discussed shortcoming is redundant: 'because I think that you know that' (line 9). This conspicuous use of mitigating devices occurs among Sweden-Swedish supervisors in particular (Nelson & Henricson 2016, Henricson & Nelson 2017.…”

Section: The Writing Counsellor As a Normative Centrementioning

confidence: 99%

OKAY as a content word: Regulating language and constructing centres of norms in Finnish, Finland-Swedish, and Sweden-Swedish academic writing consultation meetings

et al. 2023

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The focus of this article is on OKAY as a resource for regulating language and constructing norm centres in authentic consultation meetings related to academic writing and recorded in Finland and Sweden. It gives an overview of all occurrences of OKAY in the interactional data in question, revealing that the word occurs frequently in academic writing consultations in Finnish, Finland Swedish, and Sweden Swedish. There are similarities in the frequency of its use and the distribution of occurrences between counsellor and student in the Finnish and the Finland-Swedish data, whereas the Sweden-Swedish counselling interactions follow a slightly different pattern. Through the lens of conversation analysis and systemic–functional linguistics, we further demonstrate how the counsellors and the students use the evaluative content word OKAY as a resource for regulating both academic writing and the counselling interaction, and thereby position themselves epistemically and orient towards different centres of norms.

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Expressing thinking in institutional interaction: Stancetaking in mental health rehabilitation group discussions

Paananen

Stevanovic²,

Valkeapää

2021

Journal of Pragmatics

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Kognitionsverb i sverigesvenska och finlandssvenska handledningssamtal

Cited by 4 publications

References 5 publications

An Ontology for Facilitating Discussion of Catalytic Strategies of RNA-Cleaving Enzymes

An Ontology for Facilitating Discussion of Catalytic Strategies of RNA-Cleaving Enzymes

OKAY as a content word: Regulating language and constructing centres of norms in Finnish, Finland-Swedish, and Sweden-Swedish academic writing consultation meetings

Expressing thinking in institutional interaction: Stancetaking in mental health rehabilitation group discussions

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