KORELASI ANTARA HASIL TES MIKROSKOPIS DENGAN TES CEPAT MOLEKULER PADA PASIEN TUBERCULOSIS DAN MULTIDRUG RESISTEN TUBERCULOSIS DI RSUD Dr. H CHASAN BOESOIRIE TERNATE

Abstract

Tuberculosis (TB) is a pulmonary disease caused by Mycobacterium tuberculosis. Globally in 2018 theestimated number of people affected by TB was estimated at 10.0 million population and 484,000 cases ofmultidrug-resistant TB (MDR-TB). This study aims to determine the correlation between microscopic testresults with RMT on TB and MDR-TB patients at RSUD Dr. H Chasan Boesoirie Ternate. This type of researchis analytical research using a retrospective approach. The sample in this study were patients with suspected TBand MDR-TB who had performed microscopic tests and TCM in February – April at 2020 in the ClinicalPathology Laboratory of RSUD Dr. H Chasan Boesoirie Ternate, who met the inclusion and exclusion criteria.Data were analyzed using the SPSS program analysis was carried out in stages, namely by univariate andbivariate using chi-square test. From 100 samples, the results of RMT examination with TB suspects were 30rifampicin sensitive samples with 2 rifampicin resistance and 5 rifampin sensitive samples for TB MDR-TBsuspects RMT examination results. Chi-square test results obtained the value of p = 000 (p <0.05). There is stilla significant difference between the microscopic test results with RMT in TB and MDR-TB suspect patients atRSUD Dr. H Chasan Boesoirie Ternate.

Tuberculosis Surveillance System Evaluation in Blitar District: Study of System Approach and Attributes

“…Furthermore, laboratory examination using the Rapid Molecular Test (TCM) with Xpert MTB/RIF as the gold standard and further examination via lung x-ray if the TCM results are negative. The results of laboratory examinations are used as the basis for determining Tuberculosis cases (25). The sensitivity of the surveillance system can find the proportion of Tuberculosis cases used to describe the prevalence of Tuberculosis in a population.…”

Kesepakatan Hasil Pemeriksaan Tes Cepat Molekuler (TCM) dengan Pemeriksaan Mikroskopik Basil Tahan Asam (BTA) dalam Penegakkan Diagnosis Tuberkulosis Paru

“…(5) Salah satu hambatan dalam meningkatkan penemuan kasus TB Paru hingga saat ini yaitu masih adanya keterbatasan dari teknik atau metode diagnostik. (6) Hingga saat ini kultur merupakan pemeriksaan baku diagnosis TB, namun memiliki kekurangan hasil pemeriksaan yang lama. (7) Metode diagnostik TB yang sering di gunakan dilayanan primer yaitu pemeriksaan tes cepat molekuler (TCM) dan basil tahan asam (BTA).…”

Hasil diagnostik Mycobacterium tuberculosis dari sputum penderita batuk ≥ 2 minggu dengan pewarnaan Ziehl-Neelsen di Balai Besar Kesehatan Paru Masyarakat Makassar

“…Struktur tubuh tidak berkapsul serta tidak berendospora, tidak ada kemampuan serta struktur yang dapat mendorong diri mereka sendiri, berbentuk basil yang berukuran 0,2 -0,4 x 2 -10 μm [14]. Pemeriksaan BTA merupakan pemeriksaan bakteri MTB secara mikroskopis yang umumnya menggunakan metode pewarnaan Ziehl Neelsen [15]. Pewarnaan ini menggunakan beberapa zat pewarna yang berbeda antara lain carbol fuchsin, asam alkohol, dan methylen blue.…”

“…_ Filogeni: Jurnal Mahasiswa Biologi, Volume 3, Nomor 1, Januari-April 2023, hlm [12][13][14][15][16]…”