Laboratory markers for over-attenuation of mumps vaccine virus

Boriskin, Yu. S.; Kaptsova, T.I.; Lotte, V. D.; Skvortsova, O.I.; Örvell, Claes

doi:10.1016/0264-410x(88)90097-7

Vaccine

1988

DOI: 10.1016/0264-410x(88)90097-7

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Laboratory markers for over-attenuation of mumps vaccine virus

Yu. S. Boriskin¹,

T.I. Kaptsova²,

V. D. Lotte³

et al.

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Cited by 10 publications

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Mumpsimpfstoffe: Virologische Grundlagen

Ströhle

Germann

1995

Soz Pr�ventivmed

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The prevention of mumps virus infection relies on the application of live, attenuated mumps virus vaccines. The process of attenuation from a wildtype mumps isolate to a safe vaccine has been empirical. A lower degree of attenuation results in solid immunity but carries an increased risk of post-vaccination meningitis due to the vaccine strain. Currently used vaccine strains are highly attenuated and essentially free of vaccine strain induced disease. However, their immunogenicity may be lower than previously reported.

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Mumpsimpfstoffe: Virologische Grundlagen

Ströhle

Germann

1995

Soz Pr�ventivmed

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Mumps virus variants in heterogeneous mumps vaccine

Boriskin¹,

Kaptsova²,

Booth³

1993

The Lancet

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Rapid detection of mumps virus by the polymerase chain reaction

Boriskin

Booth

Yamada

1993

Journal of Virological Methods

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Laboratory markers for over-attenuation of mumps vaccine virus

Cited by 10 publications

References 11 publications

Mumpsimpfstoffe: Virologische Grundlagen

Mumpsimpfstoffe: Virologische Grundlagen

Mumps virus variants in heterogeneous mumps vaccine

Rapid detection of mumps virus by the polymerase chain reaction

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