Labour and delivery complications at birth and later mania; An Irish case register study

Indicators of fetal growth and bipolar disorder: a Danish national register-based study

“…The study is negative in the sense that we did not find any relationship between these factors and bipolar disorder, consistent with the findings from three earlier smaller studies in which cases with bipolar disorder were compared with normal controls (Verdoux & Bourgeois, 1993 ;Stober et al 1997;Browne et al 2000). The study is negative in the sense that we did not find any relationship between these factors and bipolar disorder, consistent with the findings from three earlier smaller studies in which cases with bipolar disorder were compared with normal controls (Verdoux & Bourgeois, 1993 ;Stober et al 1997;Browne et al 2000).…”

“…Obstetric complications, including indicators of fetal growth, have been associated with an increased risk of several other psychiatric disorders, such as schizophrenia (Geddes et al 1999 ;Cannon et al 2002) and autism (Bolton et al 1997 ;Larsson et al 2005). There have been only a few studies in which people with bipolar disorder and normal controls have been compared with respect to obstetric complications (Verdoux & Bourgeois, 1993 ;Stober et al 1997 ;Browne et al 2000). Most studies in this field have not focused specifically on bipolar disorder but have included the broader categories of affective psychoses or other mood disorders (Done et al 1991 ;Sacker et al 1995 ;Gunduz et al 1999 ;Hultman et al 1999 ;Bain et al 2000;Zornberg et al 2000 ;Patton et al 2004).…”

Clinical, Demographic, and Familial Correlates of Bipolar Spectrum Disorders Among Offspring of Parents With Bipolar Disorder

“…However there may be other reasons for this discrepancy given that there was not even a trend toward an association between BP and OCs in the much larger BIOS sample. It is important to note that studies of adults with BP have also yielded heterogeneous findings 39, 40…”

High Concordance of Bipolar I Disorder in a Nationwide Sample of Twins

“…The few representative studies distinguishing bipolar I disorder from unipolar depressive disorder have all had some methodological limitations (2)(3)(4). The role of environmental risk factors, such as labor and delivery complications at birth, has been controversial (5,6).…”