Lactic Acid Bacteria in the Gut in Normal and Disordered States

Abstract

The human gut flora is a complex and finely balanced ecosystem which plays an important protective role in humans. Although relatively stable, its composition may be altered in various disease states and by the administration of antimicrobial agents. Preparations containing viable lactic acid bacteria of human origin appear to have value in restoring normal microbial function and alleviating symptoms in some patients with gastrointestinal infection and other conditions.

Changes in the Intestinal Flora After the Administration of Prophylactic Antibiotics to Patients Undergoing a Gastrectomy

“…Earlier studies indicated that lactic acid-producing bacteria, such as Bifidobacterium and Lactobacillus spp., may inhibit the overgrowth of pathogenic microorganisms, stimulate immunity, and promote clinical recovery from enteric infection. [23][24][25] These organisms are used as probiotics. Lidbeck et al reported that during Lactobacillus acidophilus supplementation after clindamycin treatment, C. albicans disappeared from the intestinal flora of three of four subjects, while no decrease in the yeast occurred in patients receiving a placebo.…”

Biocontrol of Clinical Bacteria Infecting Urinogenital System by Probiotic Bacteria

“…Enterococcus faecium is a lactic acid bacterium that had antibacterial effect in vitro, It's a gram positive bacterium that has good microbiological characteristics such as short generation time and bacteriocin production (Lewenstein et al, 1979) and also has effect in gastrointestinal disorders (Salminen & Deighton, 1992).…”

Gastrointestinal Infections

“…Several clinical studies have investigated the use of probiotics as dietary supplements for the prevention and treatment of certain gastrointestinal infections (Salminen et al, 1998). Early results have not been consistent however, possibly due to the variety of preparations used, methodological problems and varying bacterial strains used in fermented products.…”