Larvicidal Effect of Marrubium Vulgare on Culexpipiens in Eastern Algeria

Amel, Aouati; Sélima, Berchi

doi:10.1016/j.egypro.2015.07.739

Cited by 11 publications

(5 citation statements)

References 16 publications

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“…The greatest mortality rate (94%) was achieved with 900 mg/L and a 72 h exposure to M. vulgare extract, whereas a 59% mortality rate was achieved with 900 mg/L and a 72 h exposure period. These results may provide an opportunity to develop alternatives to environmentally hazardous chemicals using some readily available, affordable plants which are mostly harmless to different living organisms [105]. Furthermore, the volatile oil of M. vulgare has a remarkable toxicity on the snails of both Schistosoma mansoni and S. haematobium species [106].…”

Section: Use As Natural Pesticidesmentioning

confidence: 99%

Marrubium vulgare L.: A Phytochemical and Pharmacological Overview

et al. 2020

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Marrubium vulgare is a plant with high bioactive potential. It contains marrubiin, a labdane diterpene that is characteristic for this genus, as well as a complex mixture of phenolic compounds. According to numerous studies, M. vulgare acts as a good antioxidant agent, and due to this, it could potentially be useful in treatments of cancer, diabetes mellitus, and liver diseases. In addition, its anti-inflammatory, wound-healing, antihypertensive, hypolipidemic, and sedative potential are discussed. Apart from that, its antimicrobial activity, especially against Gram+ bacteria, fungi, herpes simplex virus, and parasites such as Toxoplasma gondii, Trichomonas vaginalis, and Plasmodium berghei-berghei was recorded. Additionally, it could be used as a chicken lice repellent, herbicide, and natural insecticide against mosquito larvae and natural molluscicide. In veterinary medicine, M. vulgare can be used as an anthelmintic against the eggs and larvae of bovine strongyles parasites, and as an antibiotic against bovine mastitis caused by resistant bacterial strains. Due to the mentioned benefits, there is a tendency for the cultivation of M. vulgare in order to ensure high-quality raw material, but more firm scientific evidence and well-designed clinical trials are necessary for the well-established use of M. vulgare herb and its preparations.

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Section: Use As Natural Pesticidesmentioning

confidence: 99%

Marrubium vulgare L.: A Phytochemical and Pharmacological Overview

et al. 2020

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“…The major sesquiterpene hydrocarbon was γ-cadinene (17.68%). In another study, methanol extract of M. vulgare leaves was investigated against 4 th instar larvae of the mosquito C. pipiens L. [118]. The results of this study showed that methanolic extracts of M. vulgare are toxic to 4 th stage larvae of C. pipiens after longer exposure time for larvae.…”

Section: Molluscicidal and Mosquitocidal Activitymentioning

confidence: 90%

Marrubium vulgare L.: A review on phytochemical and pharmacological aspects

Lodhi¹,

Vadnere²,

Sharma³

et al. 2017

J Intercult Ethnopharmacol

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Marrubium vulgare L. (family: Lamiaceae), also known as the white horehound, is widely used as an herbal remedy for chronic coughs and colds. It is used in various disorders related to skin, liver, gastric, heart, and immune system. This review abridges phytochemical, pharmacological studies, and medicinal uses of M. vulgare and provides scientific proof for various ethnobotanical claims to identify gaps, which will give impulsion for novel research on M. vulgare based herbal medicines. This review summarizes selected scientific evidence on phytochemistry and pharmacological properties of M. vulgare over the past 48 years . Works related to M. vulgare was reviewed from various sources such as books, internet source, i.e., Google Search engine, PubMed, and Science Direct, and chemical abstract. The exhaustive literature was studied, and critical analysis was performed according to their phytochemical and pharmacological properties. Phytochemical investigations on different parts of M. vulgare have been reported the presence of flavonoids, steroids, terpenoids, tannins, saponins, and volatile oils (0.05%). The aerial parts contain marrubiin, together with ursolic acid and choline. Pharmacological activities such as antinociceptive, antispasmodic, antihypertensive, antidiabetic, gastroprotective, anti-inflammatory, antimicrobial, anticancer, antioxidant, and antihepatotoxic activity have been reported. M. vulgare has therapeutic potential in the treatment of inflammatory conditions, liver disorders, pain, cardiovascular, gastric, and diabetic conditions. Aerial parts of M. vulgare is a good source of labdane type diterpene especially marrubiin which is present in high concentrations. However, further scientific studies are needed to explore clinical efficacy, toxicity and to explore the therapeutic effect of major secondary metabolites such as diterpenes, phenylpropanoid, and phenylethanoid glycosides of M. vulgare.

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“…Mortality of the 4 th instar larvae of the mosquito Culex pipiens exposed to different doses of methanolic extract of Marrubium vulgare was varied with exposure time. The maximum mortalities (31, 40, 59%) were recorded for the concentration of 200, 500 and 900 mg/ml respectively, after 72 h of exposure (410) .…”

Section: Marrubium Vulgarementioning

confidence: 92%

Antiparasitic activities of medicinal plants: An overview

Ali Esmail Al-Snafi

2024

GSC Biol. Pharm. Sci.

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Several of the parasites have become resistant to chemotherapy, so alternatives are urgently required. Natural products still play an important role in therapy: between 1981 and 2006, 1,184 new drugs were registered of which 28% were natural products or their derivatives. Another 24% of the new drugs had pharmacophores (functional groups with pharmacological activity) derived from natural products. In this review, PubMed, Google Scholar, Web of Science, EBSCO, Science Direct, and Scopus were searched for medicinal plants with antiparasitic, antiprotozoal, molluscicidal and insecticidal activity to encourage identification of the active ingredients, determination of clinical efficacy, studying of pharmacokinetic characteristics, investigation of the mode of action and safety.

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Larvicidal Effect of Marrubium Vulgare on Culexpipiens in Eastern Algeria

Cited by 11 publications

References 16 publications

Marrubium vulgare L.: A Phytochemical and Pharmacological Overview

Marrubium vulgare L.: A Phytochemical and Pharmacological Overview

Marrubium vulgare L.: A review on phytochemical and pharmacological aspects

Antiparasitic activities of medicinal plants: An overview

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