This paper presents a new placement and routing method for layout generation of CMOS operational amplifiers (op-amps). Both circuit sizing and layout generation stages are performed automatically. In the proposed method, layout effects are considered during the layout generation. Layout parasitics and geometry information are extracted from a new automated layout generator. In this method, the multi-objective evolutionary algorithm based on decomposition (MOEA/D) is used as an optimization algorithm. In order to verify the performance of the proposed method, the design of three-stage operational amplifier (op-amp) and two-stage class-AB operational trans-conductance amplifier (OTA) in a 0.18µm process CMOS technology with 1.8 V supply voltage are presented. The simulation results indicate the efficiency of the proposed analog layout generation method.