Laser speckle imaging to improve clinical outcomes for patients with trigeminal neuralgia undergoing radiofrequency thermocoagulation

Ringkamp, Matthias; Wooten, Matthew; Carson, Benjamin S.; Lim, Michael; Hartke, Timothy; Guarnieri, Michael

doi:10.3171/2015.1.jns14408

Cited by 8 publications

(3 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…LSCI has become a valuable and powerful tool to investigate the fast change in microcirculation blood flow because of safety, wide measurement range, good reliability, high stability, and strong practicability. [37][38][39][40] Patient populations, such as those with peripheral vascular disease, those receiving vasodilator drugs prior to surgery, or those with infected toenails might have altered the BFI values and thus require separate determination.…”

Section: Discussionmentioning

confidence: 99%

Predicting successful lumbar plexus block using blood flow index measured by laser speckle contrast imaging

Liu

et al. 2019

Preprint

View full text Add to dashboard Cite

Background: Laser speckle contrast imaging (LSCI) is a powerful optical imaging technique for real-time and dynamic measurement of regional blood flow. The objective of this prospective observational study was to investigate blood flow after changes blockade of lumbar plexus or its three major branches respectively, with LSCI technique.Methods: This study included 47 adult patients scheduled for elective lower limb surgery. For the selective blockade of lumbar plexus, femoral nerve, obturator nerve, and lateral femoral cutaneous nerve, blood flow images and pinprick sensory scores of the blocked lower limb were recorded 5 min pre block and every 5 min for 30 min post block. Blood flow index (BFI) values of toes were calculated by LSCI software.Results: In this study, we have 21 cases of successful lumbar plexus blocks, 2 cases of failed lumbar plexus block, 8 cases of successful femoral nerve blocks, 8 cases of successful obturator nerve blocks, and 8 cases of successful lateral femoral cutaneous nerve blocks. The BFI values of all five toes were significantly increased as early as 5 min after successful lumbar plexus block, whereas no signiﬁcant difference was found in BFI values after failed lumbar plexus block. BFI changes after successful selective blockade of femoral nerve, obturator nerve, or lateral femoral cutaneous nerve were negligible. BFI value of the big toe at 5 min after the successful lumbar plexus block was increased by 2.57 fold compared with the baseline value, which represented the highest increase among five tested toes. BFI value of the big toe at 10 min after lumbar plexus block showed great power to predict block outcome with a sensitivity of 100% and a speciﬁcity of 100%. The optimal cut-off value given by ROC analysis was 22.11 PU.Conclusions: Increased blood flow index measured by laser speckle contrast imaging is a reliable indicator of successful lumbar plexus block, but cannot indicate successful selective blocks of three major branches of the lumbar plexus. BFI value of the big toe at 10 min after lumbar plexus block could well predict block outcome with the cut-off value of 22.11 PU.Trial registration: NCT03169517 (Date of registration: May 25, 2017).

show abstract

Section: Discussionmentioning

confidence: 99%

Predicting successful lumbar plexus block using blood flow index measured by laser speckle contrast imaging

Liu

et al. 2019

Preprint

View full text Add to dashboard Cite

show abstract

“…Some studies showed the blood flow/perfusion around targeted muscles could be measured by using LSCI, so that the muscle microcirculation could be analyzed [ 20 , 21 ]. The LSCI also showed some good findings for assessment of pain-related blood perfusion [ 22 , 23 ]. Thus, the LSCI would be an additional way to reveal the mechanism of HSP.…”

Section: Introductionmentioning

confidence: 99%

Analysis of Muscular Electrical Activity and Blood Perfusion of Upper Extremity in Patients with Hemiplegic Shoulder Pain: A Pilot Study

et al. 2022

View full text Add to dashboard Cite

Background. Hemiplegic shoulder pain (HSP) is a common symptom for post-stroke patients, which has a severely adverse impact on their rehabilitation outcomes. However, the cause of HSP has not been clearly identified due to its complicated multifactorial etiologies. As possible causes of HSP, the abnormality of both muscular electrical activity and blood perfusion remains lack of investigations. Objective. This study aimed to analyze the alteration of muscular electrical activity and blood perfusion of upper extremity in patients with HSP by using surface electromyography (sEMG) and laser speckle contrast imaging (LSCI) measurement techniques, which may provide some insight into the etiology of HSP. Methods. In this observational and cross-sectional study, three groups of participants were recruited. They were hemiplegic patients with shoulder pain (HSP group), hemiplegic patients without shoulder pain (HNSP group), and healthy participants (Healthy group). The sEMG data and blood perfusion data were collected from all the subjects and used to compute three different physiological measures, the root-mean-square (RMS) and median-frequency (MDF) parameters of sEMG recordings, and the perfusion unit (PU) parameter of blood perfusion imaging. Results. The RMS parameter of sEMG showed significant difference ( p < 0.05 ) in the affected side between HSP, HNSP, and Healthy groups. The MDF parameter of sEMG and PU parameter of blood perfusion showed no significant difference in both sides among the three groups ( p > 0.05 ). The RMS parameter of sEMG showed a statistically significant correlation with the pain intensity ( r = -0.691, p =0.012). Conclusion. This study indicated that the muscular electrical activity of upper extremity had a correlation with the presence of HSP, and the blood perfusion seemed to be no such correlation. The findings of the study suggested an alternative way to explore the mechanism and treatment of HSP.

show abstract

“…In addition, TTFM cannot map the spatial distribution of the blood flow velocity. Since LSCI has been widely attempted in many clinical and biomedical applications during recent years [14][15][16], the LSCI technology is promising to detect the flow of the CA and has not been reported. In this study, to obtain a more accurate assessment of the pulsatile flow of the CA, we developed a speckle triangle assessment using the LSCI model: the speckle flow index (SFI), mean flow index (MFI), and pulsatility index (PI).…”

Section: Introductionmentioning

confidence: 99%

Pulsatile Flow Measurement by a Speckle Triangle Assessment

Yuan

Gao

et al. 2021

Front. Phys.

View full text Add to dashboard Cite

The blood flow in the coronary artery (CA) is pulsatile and much higher than that measured in the brain, retina, and skin before. Its quantitative measurement is medically significant in the coronary artery bypass grafting (CABG). Here, to the best of our knowledge, we first detect the pulsatile flow using the laser speckle contrast imaging technique. Since the factors influencing the flow rate in the CA are complex, we developed a comprehensive model, a speckle triangle assessment (STA), to assess the characteristics of the flow: the speckle flow index (SFI), mean flow index (MFI), and pulsatility index (PI). The phantom experiment was performed and found that our customized setup possessed high dynamic range of the velocity measurement with good sensitivity. It also indicated that the pulsatile flow estimated by the speckle triangle assessment is promising to obtain a more accurate assessment of a coronary artery’s patency in the CABG.

show abstract

Laser speckle imaging to improve clinical outcomes for patients with trigeminal neuralgia undergoing radiofrequency thermocoagulation

Abstract: Noninvasive laser speckle imaging can be performed safely in nonhuman primates. Because improved probe placement may reduce morbidity associated with percutaneous rhizotomies, efficacy trials of laser speckle imaging should be conducted in humans.

Cited by 8 publications

References 24 publications

Predicting successful lumbar plexus block using blood flow index measured by laser speckle contrast imaging

Predicting successful lumbar plexus block using blood flow index measured by laser speckle contrast imaging

Analysis of Muscular Electrical Activity and Blood Perfusion of Upper Extremity in Patients with Hemiplegic Shoulder Pain: A Pilot Study

Pulsatile Flow Measurement by a Speckle Triangle Assessment

Contact Info

Product

Resources

About