Late recurrence of a hepatic angiomyolipoma

Croquet, Vincent; Pilette, Christophe; Aubé, Christophe; B, Bouju; Oberti, Frédéric; Cervi, Charles; Arnaud, Jean‐Pierre; Rousselet, Marie‐Christine; Boyer, J.; Calès, Paul

doi:10.1097/00042737-200012050-00018

Cited by 51 publications

(23 citation statements)

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“…Although postoperative recurrence occurred in one patient, the tumor recurred in a different lobe and almost a decade after the first surgery. Two similar cases were reported by other researchers, in which the tumors recurred 3 and 6 years after surgery [7,8]. Together, these three cases of recurrence suggest the possibility that hepatic AML may be of multifocal origin and this evidence appears to support the viewpoint that hepatic AML can be treated by nonsurgical methods.…”

Section: Discussionsupporting

confidence: 84%

“…While it has been widely believed that hepatic AML is a benign tumor that can be managed by nonsurgical approaches, more recent research has revealed that this tumor has the potential for recurrence and malignant transformation [7][8][9][10][11][12]. Therefore, significant controversy exists regarding the treatment of choice for hepatic AML.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Hepatic Angiomyolipoma: A Clinical Experience in Diagnosis and Treatment

et al. 2010

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Hepatic angiomyolipoma should be suspected in liver tumor patients with normal α-fetoprotein levels and no concomitant hepatitis. Preoperative MRI combined with percutaneous fine-needle biopsy should be the diagnostic methods of choice. Small hepatic AML proved through pathologic examination (<5 cm) may be managed by observation with close follow-up, but surgery is indicated in patients suffering from large tumors or significantly larger tumors during follow-up.

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Section: Discussionsupporting

confidence: 84%

Section: Introductionmentioning

confidence: 99%

Hepatic Angiomyolipoma: A Clinical Experience in Diagnosis and Treatment

et al. 2010

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“…[5][6][7] Tumors vary considerably in size, lesions ranging from few millimeters to as large as 36 cm have been reported. [2][3][4] Most HAMLs are solitary but multifocal tumors have been reported in association with the hereditary disease tuberous sclerosis.…”

Section: Discussionmentioning

confidence: 99%

Epithelioid angiomyolipoma of the liver with striking giant cell component: Fine‐needle aspiration biopsy findings of a rare neoplasm

Alatassi

Sahoo

2009

Diagnostic Cytopathology

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Angiomyolipoma (AML) is a uncommon benign neoplasm of the liver with cyto- and histologic features similar to the more commonly encountered renal AML. Tumors composed predominantly of epithelioid cells have been referred to as epithelioid AML. Because most liver lesions are first evaluated by fine-needle aspiration biopsy (FNAB), it is important to distinguish this variant of AML from more common hepatic neoplasms such as hepatocellular carcinoma (HCC) or metastatic tumors. Rare reports of epithelioid AML of the liver diagnosed by FNAB are in the literature. Here, we describe the cytologic findings of a unique case of epithelioid AML with numerous giant cells.

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“…To complicate matters, hepatic angiomyolipoma has a resemblance to hepatocellular carcinoma in clinical presentation. Both can be single or multiple, can recur, 21 and can change in size and composition, as described by some authors, 22 however, in the proper clinical settings, this should not raise unnecessary suspicion.…”

Section: Discussionmentioning

confidence: 95%